Changes in thyroid function status of suicidal patients

  • Shazia Khurshid Government College University; Department of Chemistry
  • Muhammad Pervaiz Government College University; Department of Chemistry
  • Sareen Akhtar Government College University; Department of Chemistry
  • Shan Elahi Mayo Hospital; Centre for Nuclear Medicine (CENUM)
  • Asma Zaidi COMSATS Institute of Information Technology; Department of Chemistry
  • Zohaib Saeed Government College University; Department of Chemistry
  • Syed Majid Bukhari COMSATS Institute of Information Technology; Department of Chemistry
Keywords: Suicide, thyroid hormone, psychiatric patients, depression

Abstract

Background This study was carried out at Punjab Institute of Mental Health and Centre for Nuclear Medicine Mayo Hospital, Lahore. It is aimed at the possible association of thyroid malfunctioning with suicide attempts of patients. Objective Determination of thyroid function status of suicidal psychiatric patients and their comparison with psychiatric patients without suicide attempt or ideation. Methods Total 54 patients with either past history of suicide attempt or current suicidal ideation were selected for analysis of their thyroid function status (age 15-55 years). Age matched 50 non-suicide psychiatric patients were included for comparison. Results Two patients with suicide attempt had overt thyroid dysfunction. Remaining patients had serum FT4, FT3 and TSH level within normal range. Suicide attempter patients had lower FT4 but increased FT3 and TSH levels compared to suicidal ideation patients. Serum FT4 and TSH levels in suicidal patients were not different from psychiatric patients. Serum FT3 in suicidal patients was lower than psychiatric patients (3.7 ± 0.8 vs. 4.3 ± 0.5; p < 0.05). Female suicidal patients had lower FT3 levels compared to male patients (3.4 ± 0.6 vs. 3.9 ± 0.8 pmol/L; p < 0.05). Discussion Local suicidal patients have higher incidence of overt thyroid disorder and lower FT3 levels compared to non-suicidal psychiatric patients.

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Published
2018-02-01
How to Cite
Khurshid, S., Pervaiz, M., Akhtar, S., Elahi, S., Zaidi, A., Saeed, Z., & Bukhari, S. (2018). Changes in thyroid function status of suicidal patients. Archives of Clinical Psychiatry, 45(1), 12-14. https://doi.org/10.1590/0101-60830000000147
Section
Original Articles