Sporadic early onset Alzheimer´s disease

Authors

  • Annibal Truzzi Universidade Federal do Rio de Janeiro; Instituto de Psiquiatria
  • Jerson Laks Universidade Federal do Rio de Janeiro; IPUB; Centro para Pessoas com Doença de Alzheimer e outros Transtornos Mentais da Velhice

DOI:

https://doi.org/10.1590/S0101-60832005000100006

Keywords:

Alzheimer's disease, presenile

Abstract

Alzheimer's disease (AD) is the main cause of dementia. A subgroup of patients has the familial or early-onset (<65 years) form of AD, with rapid course and a dominant genetic transmission through many generations. We report a case of a patient without a positive familiar history for AD, who presented early memory problems and progressive functional and cognitive (speech, praxis, executive functions e viso-spatial habilities) decline. Behavioural (imnsonia, psychomotor agitation and hypersexuality) and psychological (depression) symptoms of AD were noticed in different stages of the disease. Structural and functional neuroimaging techniques showed impairment of posterior cortical areas. Early onset AD can be confounded with psychiatric disorders especially when there is no familiar history for AD. The presenile impact on both patient and family is intense and treatment in the early stages is very important to reduce patient and caregivers' burden.

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Published

2005-01-01

Issue

Vol. 32 No. 1 (2005)

Section

Case Reports

License

Once accepted for publication, the manuscript becomes permanent property of the Archives of Clinical Psychiatry. This copyright transfer subsumes exclusive and unlimited entitlement of the Archives of Clinical Psychiatry to publish and distribute the full contents of articles in whichever publishing medium, including press and electronic media, in Brazil and abroad.

Manuscripts are accepted with the understanding that the Editor and the editorial staff have the right to make revisions aimed at greater conciseness, clarity, and conformity with Journal style, of course without changing its content.

How to Cite

Sporadic early onset Alzheimer´s disease . (2005). Archives of Clinical Psychiatry, 32(1), 43-46. https://doi.org/10.1590/S0101-60832005000100006