Major depression and hormone suppression: response with nortriptiline

Authors

  • Livia Mitsue Gomes Yukizaki Universidade Federal do Rio de Janeiro
  • André Barciela Veras Universidade Federal do Rio de Janeiro; Instituto de Psiquiatria; Programa de Pós-Graduação
  • Flávia Schueler Franco Universidade Federal do Rio de Janeiro
  • Luisa Duarte Novo Universidade Federal do Rio de Janeiro
  • Arabella Rassi Universidade Federal do Rio de Janeiro; Instituto de Psiquiatria; Programa de Pós-Graduação
  • Antonio Egídio Nardi Universidade Federal do Rio de Janeiro; Faculdade de Medicina; Instituto de Psiquiatria

DOI:

https://doi.org/10.1590/S0101-60832007000500006

Keywords:

Endometriosis, goserelin, nortriptyline, depression, anxiety

Abstract

BACKGROUND: The relevance of this clinical case report is to emphasize the importance of the use of nortryptiline for major depression after endometriosis treatment. OBJECTIVE: To describe by a case report the relationship between treatment for endometriosis and psychiatric disorders. We will also describe the therapeutic response to nortriptyline. METHODS: Psychiatric interview and periodical clinical psychiatric evaluation for the treatment of a patient in the Outpatient Unit of the Institute of Psychiatry of the Federal University of Rio de Janeiro. RESULTS: An outpatient, fifty-five year-old woman with major depression treated in the Psychiatric Institute of Federal University of Rio de Janeiro. She was being treated for endometriosis with goserelin for hormone suppression when she started to complain of depressive and anxiety symptoms. The patient did not improve with 20 mg/day of fluoxetine for 8 weeks. She improved after 2 weeks using 25 mg/day of nortryptiline. The improvement persisted during our 16 weeks follow-up. CONCLUSION: Although only sertraline has its efficacy demonstrated for depressive symptoms associated with ovarian suppression, in this case nortriptyline was efficient too. We observed the necessity of more studies about this topic in order to better evaluate other therapeutic options.

Downloads

Download data is not yet available.

Published

2007-01-01

Issue

Section

Case Reports

How to Cite

Major depression and hormone suppression: response with nortriptiline . (2007). Archives of Clinical Psychiatry, 34(5), 243-245. https://doi.org/10.1590/S0101-60832007000500006