Carbon nanotubes applied in neuroscience: prospects and challenges

Authors

  • Virginia Oliveira Universidade Federal de Juiz de Fora; Faculdade de Farmácia
  • Michele Munk Pereira Universidade Federal de Juiz de Fora; Faculdade de Farmácia
  • Humberto de Mello Brandão Embrapa Gado de Leite
  • Marcos Antônio Fernandes Brandão Universidade Federal de Juiz de Fora; Faculdade de Farmácia
  • Wagner Farid Gattaz Universidade de São Paulo; Faculdade de Medicina; Departamento e Instituto de Psiquiatria; Laboratório de Neurociências
  • Nádia Rezende Barbosa Raposo Universidade de São Paulo; Faculdade de Medicina; Departamento e Instituto de Psiquiatria; Laboratório de Neurociências

DOI:

https://doi.org/10.1590/S0101-60832011000500006

Keywords:

Carbon nanotubes, drug delivery, electrical interface, tissue regeneration, neurobiology

Abstract

BACKGROUND: Carbon nanotubes (CNTs) are the most promising nanomaterials for therapeutic application in neurodegenerative diseases. Potential applications include systems for controlled drug delivery, electrical interfaces and substrates for cell growth. OBJECTIVE: To describe the state of art, prospects and challenges of applying CNTs in neuroscience. METHODS: There has been systematic search in Medline, Lilacs and SciELO, using the keywords "carbon nanotubes", "drug delivery", "electrical interface", "tissue regeneration", "neuroscience", "nanotechnology" and "biocompatibility", properly grouped. RESULTS: The literature review showed controversies in studies on the biocompatibility of CNTs, although it has ratified its potential for neuromedicine and neuroscience. DISCUSSION: These results highlight the need for modeling studies on the applications and interactions of nanostructures with biological systems.

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Published

2011-01-01

Issue

Section

Review

How to Cite

Carbon nanotubes applied in neuroscience: prospects and challenges . (2011). Archives of Clinical Psychiatry, 38(5), 201-206. https://doi.org/10.1590/S0101-60832011000500006