Awareness of disease in Alzheimer's disease: preliminary results of a longitudinal study
DOI:
https://doi.org/10.1590/S0101-60832011000200003Keywords:
Dementia, anosognosia, awareness of deficit, insightAbstract
BACKGROUND: The presence of cognitive deficits and behavioral and psychological symptoms in dementia makes the phenomenon of awareness of disease a rather complex object of study. This phenomenon has been most studied in cross-sectional studies than in longitudinal studies. OBJECTIVE: To compare awareness of disease in Alzheimer's patients over six months. METHODS: Early-stage Alzheimer's disease patients (n = 18) were evaluated over six months using Scale of Psychosocial Impact of the Diagnosis of Dementia (ASPIDD), Mini Mental State Examination (MMSE), Clinical Dementia Rating (CDR), Cornell Depression Scale in Dementia (Cornell), Quality of Life in Alzheimer's Disease (QoL-AD - patient's version) and Pfeffer Functional Activities Questionnaire (PFAQ) and caregivers were assessed using Zarit Burden Interview (Zarit) and QoL-AD - caregiver's version. RESULTS: At six months' observation, there was a decline in the degree of awareness of disease (p = 0,02), in cognitive status (p < 0.01), in functional activities (p < 0.01), in clinical staging of the dementia (p < 0.01) and an increase in depressive symptoms (p < 0.01). DISCUSSION: As the severity of dementia increases, there is also impaired awareness of disease, together with cognitive and functional deficits.Downloads
Download data is not yet available.
Downloads
Published
2011-01-01
Issue
Section
Original Articles
License
Once accepted for publication, the manuscript becomes permanent property of the Archives of Clinical Psychiatry. This copyright transfer subsumes exclusive and unlimited entitlement of the Archives of Clinical Psychiatry to publish and distribute the full contents of articles in whichever publishing medium, including press and electronic media, in Brazil and abroad.
Manuscripts are accepted with the understanding that the Editor and the editorial staff have the right to make revisions aimed at greater conciseness, clarity, and conformity with Journal style, of course without changing its content.
How to Cite
Awareness of disease in Alzheimer’s disease: preliminary results of a longitudinal study . (2011). Archives of Clinical Psychiatry, 38(2), 57-60. https://doi.org/10.1590/S0101-60832011000200003