Malignant ameloblastoma

a challenging diagnosis

  • Ayodeji Salamia Department of Pathology, University of Ibadan
  • Uchenna Ezenkwa Department of Pathology, University College Hospital
  • Mudashiru Salami Department of Cardiothoracic Surgery, University of Ibadan
  • Mustapha Ajani Department of Pathology, Babcock University
  • Clement Okolo Department of Pathology, University of Ibadan
Keywords: Ameloblastoma, Mediastinum, Neoplasm Metastasis, Pulmonary Atelectasis


Ameloblastoma is an uncommon and locally aggressive, benign, odontogenic tumor, with local recurrence when not adequately excised. A rare variant of this neoplasm with the benign features but accompanied with metastases has been described. This rare variant is malignant ameloblastoma and is known to have a poor prognosis. We present the case of a young woman who had recurrent mandibular tumors, which were resected twice and histologically reported as ameloblastoma. Four years later, she presented with pulmonary metastasis and atelectasis. A review of the literature on this very rare neoplasm was also performed.


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How to Cite
Salamia, A., Ezenkwa, U., Salami, M., Ajani, M., & Okolo, C. (2018). Malignant ameloblastoma. Autopsy and Case Reports, 8(4), e2018043. Retrieved from
Article / Autopsy Case Report