Ameloblastoma with distinctive granular cell pattern

an 8 case study

Authors

  • Ana Maria Hoyos Cadavid Universidade de São Paulo, School of Dentistry
  • Tathyane Harumi Nakajima Teshima Universidade de São Paulo, School of Dentistry
  • Clóvis Antônio Lopes Pinto AC Camargo Cancer Center
  • Cláudia Malheiros Coutinho Camillo AC Camargo Cancer Center
  • Silvia Vanessa Lourenço

Keywords:

Ameloblastoma, Odontogenic Tumors, Neoplasms

Abstract

Ameloblastoma with granular cell pattern (AGC) is classified as an unusual histological subtype of solid/multicystic ameloblastoma, characterized by granular changes in stellate-like cells located within the inner portion of the epithelial follicles. Studies have revealed that lysosomal overload causes cytoplasmic granularity; however, the mechanism involved remains poorly understood. Here we report on eight cases of granular cell ameloblastoma, in the posterior region of the mandible. The age of the patients included in this case series ranged from 35 -64 years old and 87.5% of cases occurred in non-Caucasians, with a slight gender predilection for men (62.5%). There was no evidence of recurrence, and the majority of the cases were treated with surgical resection (87.5%). All tumors displayed histopathological features consistent with the diagnosis of ameloblastoma with granular cell pattern.

Downloads

Download data is not yet available.

Downloads

Published

2018-11-12

Issue

Vol. 8 No. 4 (2018)

Section

Article / Clinical Case Report

License

Authors of articles published by Autopsy and Case Report retain the copyright of their work without restrictions, licensing it under the Creative Commons Attribution License - CC-BY, which allows articles to be re-used and re-distributed without restriction, as long as the original work is correctly cited.

How to Cite

Cadavid, A. M. H., Teshima, T. H. N., Pinto, C. A. L., Camillo, C. M. C., & Lourenço, S. V. (2018). Ameloblastoma with distinctive granular cell pattern: an 8 case study. Autopsy and Case Reports, 8(4), e2018052. https://revistas.usp.br/autopsy/article/view/151749