Intravascular large B-cell lymphoma: The Great Imitator

Authors

  • Katherine Ann Devitt University of Vermont Medical Center, Department of Pathology and Laboratory Medicine
  • Juli-Anne Gardner University of Vermont Medical Center, Department of Pathology and Laboratory Medicine

DOI:

https://doi.org/10.4322/acr.2018.055

Keywords:

Lymphoma, non-Hodgkin, B-cell, Ehrlichiosis, Blood Vessels, Autopsy

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma with an estimated incidence of less than one per million. Unlike other hematopoietic malignancies, lymphadenopathy and hepatosplenomegaly are uncommon, and patients typically present with nonspecific symptoms. IVLBCL presents a diagnostic challenge and patients are usually diagnosed late in the disease course, if at all, and the prognosis is poor. The differential diagnosis is broad, and physicians often pursue multiple diagnostic possibilities during patient workup. We present a case of IVLBCL discovered at autopsy in an 80-year-old male who presented with history and symptoms pointing to the tick-borne illness ehrlichiosis.

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Published

2019-10-07

How to Cite

Devitt, K. A., & Gardner, J.-A. (2019). Intravascular large B-cell lymphoma: The Great Imitator. Autopsy and Case Reports, 8(4), e2018055. https://doi.org/10.4322/acr.2018.055

Issue

Vol. 8 No. 4 (2018)

Section

Article / Autopsy Case Report

License

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