An inferior sinus venosus interatrial communication associated with a secundum atrial septal defect, clinically presenting in an adult patient: autopsy report
AbstractAtrial septal defects (ASD) are the most common congenital cardiac lesion
in adults, representing up to 40% of acyanotic shunt lesions in patients older
than 40 years. Secundum ASD comprises defects in the area of the oval
fossa, and may be associated with other types of interatrial communications.
We present a case of a 25 year-old female patient who was asymptomatic
until the age 22 when she started presenting exertion dyspnea and lower
limbs edema, during her third pregnancy. The patient was admitted in the
emergency department because of a febrile respiratory distress syndrome
dying in less than 36 hours after her arrival. The autopsy examination revealed
pneumonia and a secundum ASD, associated with a rare form of interatrial
communication, the inferior sinus venosus defect, which is characterized by
an anomalous connection of the right pulmonary veins to the inferior caval vein
at its opening in the right atrial cavity, while retaining partially their connection
to the left atrium. A dysplastic and thickened mitral valve was also present.
Signs of pulmonary hypertension confirm the Eisenmenger syndrome in this
Copyright (c) 2017 Autopsy and Case Reports
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright and publishing license
Authors retain copyright granting the journal right of first publication with the work simultaneously licensed under the Creative Commons Attribution Non-Commercial License.
Autopsy and Case Reports accepted articles are published under the Creative Commons Attribution Non-Commercial License. Under this License, the authors agree to have the CC-BY-NC license applied to their work, which retains the author's ownership of the copyright for their article and permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original authors and source are properly cited. This facilitates freedom in re-use and also ensures that the journal's content can be mined without barriers for the needs of research.