Malignant paratesticular mesothelioma

  • Leonardo Gomes da Fonseca Departamento de Oncologia do Instituto do Câncer do Estado de São Paulo
  • Daniel Fernandes Marques Departamento de Oncologia do Instituto do Câncer do Estado de São Paulo
  • Tiago Kenji Takahashi Departamento de Oncologia do Instituto do Câncer do Estado de São Paulo
  • Fernando Nalesso Aguiar Departamento de Oncologia do Instituto do Câncer do Estado de São Paulo
  • Juliana Naves Ravanini Departamento de Patologia do Instituto do Câncer do Estado de São Paulo
  • Daniel Fernandes Saragiotto Departamento de Oncologia do Instituto do Câncer do Estado de São Paulo
Keywords: Mesothelioma, Chemotherapy, Adjuvant, Spermatic cord, Orchiectomy.

Abstract

Mesothelioma of the tunica vaginalis testis (MTVT) is a rare tumor that usually affects patients after the sixth decade of life. Exposure to asbestos is a known risk factor. Enlargement of the scrotal volume is the most common initial clinical manifestation, and about 15% of cases present metastasis at diagnosis. The treatment relies on surgical resection while the role of adjuvant chemotherapy and radiotherapy remains unclear. The prognosis for patients is generally poor, with a lethal outcome in 30% over a 24-month period. The authors report a case of a 62-year-old patient with the diagnosis of MTVT without a history of asbestos exposure. After surgical treatment, metastatic disease ensued. Chemotherapy was initiated, but could not be continued due to marked and fast clinical deterioration. The authors call attention to the difficulty of early diagnosis of MTVT due to a nonspecific clinical picture, the lack of action by the patient when the scrotal enlargement was first noticed, and the lack of tumor markers. Delayed diagnosis is definitely related to unfavorable prognosis.

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Published
2014-03-31
How to Cite
Fonseca, L., Marques, D., Takahashi, T., Aguiar, F., Ravanini, J., & Saragiotto, D. (2014). Malignant paratesticular mesothelioma. Autopsy and Case Reports, 4(1), 45-51. https://doi.org/10.4322/acr.%y.81210
Section
Article / Clinical Case Report