Minimally invasive autopsies: a promise to revive the procedure
AbstractSince ancient times, the autopsy has been a relevant source for the improvement of technical and scientific knowledge in the health area. From the first anatomic studies in the Middle Ages to the use of modern molecular techniques for the study of physiopathological processes, the autopsy has proven to be a very rich source of material and inspiration for the advancement of scientific knowledge. However, in recent decades, there has been a marked decline in medical autopsies—a situation that has important implications in research as well as education in medical sciences. For instance, the decline in the number of autopsies makes it difficult to apply the modern techniques of molecular biology and pathology in certain diseases of organs where tissue sampling is very difficult or not possible during life. Dementia and the characterization of the toxic effects of chemotherapy on the heart are classical examples of this situation. Also, systemic diseases that do not need a biopsy to achieve the diagnosis, such as obesity and metabolic syndromes, have become epidemic nowadays and could be better explained if researchers have access to adipose tissue sampled from different locations; for example, coronary and carotid arteries as well as pancreatic tissue, a situation rarely indicated during life.
Copyright (c) 2017 Autopsy and Case Reports
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright and publishing license
Authors retain copyright granting the journal right of first publication with the work simultaneously licensed under the Creative Commons Attribution Non-Commercial License.
Autopsy and Case Reports accepted articles are published under the Creative Commons Attribution Non-Commercial License. Under this License, the authors agree to have the CC-BY-NC license applied to their work, which retains the author's ownership of the copyright for their article and permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original authors and source are properly cited. This facilitates freedom in re-use and also ensures that the journal's content can be mined without barriers for the needs of research.