Sister Mary Joseph nodule: it does not bode well

  • Stephen A. Geller Department of Pathology and Laboratory Medicine – David Geffen School of Medicine – University of California, Los Angeles/CA
  • Fernando Peixoto Ferraz de Campos Department of Internal Medicine – Hospital Universitário – Universidade de São Paulo, São Paulo/SP


Sister Mary Joseph, the superintendent nurse and surgical assistant of Dr. William Mayo at St Mary’s Hospital (presently Mayo Clinic), was the first to note the association of umbilical nodules with intra-abdominal malignancy. Dr. Hamilton Bailey, a British surgeon, in his classic book Physical Signs in Clinical Surgery named the lesion for Sister Mary Joseph; the palpable bulging usually firm nodule distorting and invading into the umbilicus as a manifestation of metastatic malignancy from the abdomen or the pelvis.


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How to Cite
Geller, S., & Campos, F. (2014). Sister Mary Joseph nodule: it does not bode well. Autopsy and Case Reports, 4(3), 5-7.
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