The post-mortem diagnosis of vasocclusive crisis in sickle cell disease

Authors

  • Varsha Bhatia Department of Pathology – Grant Government Medical College, Mumbai
  • Richa Juneja Department of Pathology – Grant Government Medical College, Mumbai
  • Vijay Juvekar Department of Pathology – Grant Government Medical College, Mumbai

DOI:

https://doi.org/10.4322/acr.%25y.98472

Abstract

Sickle cell disease (SCD) comprises a group of genetic blood disorders that affect the hemoglobin molecular structure, and in some cases, the association with hemoglobin synthesis. In sickle cell anemia, the replacement of glutamic acid by valine at the 6th position on the beta chain from the N terminal results in the synthesis of the abnormal hemoglobin, called hemoglobin S (HbS).

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Published

2014-09-30

Issue

Section

Letters to the Editor

How to Cite

The post-mortem diagnosis of vasocclusive crisis in sickle cell disease. (2014). Autopsy and Case Reports, 4(3), 9-11. https://doi.org/10.4322/acr.%y.98472