Association of hypertension and dyslipidaemia with increasing obesity in patients with Type 2 Diabetes Mellitus

  • Zikria Saleem University of the Punjab, University College of Pharmacy, Department of Clinical Pharmacy
  • Hamid Saeed University of the Punjab, University College of Pharmacy, Department of Clinical Pharmacy
  • Zohaib Abbas Khan University of the Punjab, University College of Pharmacy, Department of Pharmacology
  • Muhammad Imran Hassan Khan Lahore General Hospital, Diabetes, Endocrine and Metabolic Centre (DEMC)
  • Furqan Khurshid Hashmi University of the Punjab, University College of Pharmacy, Department of Clinical Pharmacy
  • Muhammad Islam University of the Punjab, University College of Pharmacy, Department of Clinical Pharmacy
  • Afzaal Bashir King Edward Medical University (KEMU)
  • Saleha Sadeeqa Lahore College for Women University, Institute of Pharmacy
Keywords: Type II Diabetes Mellitus, Dyslipidaemia, Obesity, HbA1c, Lahore/Pakistan

Abstract

The study was performed to estimate the association of hypertension and dyslipidaemia with increasing body weight and obesity in Type II diabetics of Lahore, Pakistan. An observational study was conducted by enrolling 2708 obese diabetics from four diabetes care centres of Lahore, Pakistan. Data was collected for a period of 7 months. Associations were estimated using chi-square, binary and multinomial logistic regression. Data suggested that blood pressure, systolic and diastolic, exhibited continual increase with increasing body weight and obesity class in diabetes patients with 41.8% increase in the prevalence of hypertension in obesity class III subjects (OR; 1.91, p=0.02). Likewise, triglycerides and total cholesterol exhibited continual increase in their mean values with increasing obesity, i-e., an overall increase in the prevalence of dyslipidaemia of 27.2% in obesity class 3 subjects (OR; 1.94, p=0.29). Taken together, this data suggested that hypertension is potentially associated with increasing obesity in diabetics, while dyslipidaemia demonstrated plausible association only with obesity class 3.

Downloads

Download data is not yet available.
Published
2019-08-07
How to Cite
Saleem, Z., Saeed, H., Khan, Z., Khan, M., Hashmi, F., Islam, M., Bashir, A., & Sadeeqa, S. (2019). Association of hypertension and dyslipidaemia with increasing obesity in patients with Type 2 Diabetes Mellitus. Brazilian Journal of Pharmaceutical Sciences, 55, e18136. https://doi.org/10.1590/s2175-97902019000118136
Section
Articles