The importance of clinical, histopathological and immunohistochemical marking for differential diagnosis of non-hematopoietic gastrointestinal mesenchymal neoplasms in dogs: literature review

  • Rafael Magdanelo Leandro Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia http://orcid.org/0000-0002-1381-1553
  • Fernando de Paula Freitas Universidade Anhanguera, Hospital Veterinário, Departamento de Cirurgia
  • Lilian Rose Marques de Sá Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia
Keywords: C-KIT, Sarcoma, Stomach, Intestine, Colon, Rectum

Abstract

Gastrointestinal neoplasms in dogs represent a challenge for the veterinary clinician and surgeon as they are mostly malignant and when the owner notices the primary clinical changes the disease may already be in an advanced stage. Due to the high clinical and histopathological similarity between mesenchymal gastrointestinal neoplasms, it is often impossible to establish the definitive morphological diagnosis using light microscopy alone. In addition, there are only a few articles describing the anatomopathological and immunohistochemical characteristics, which make its complete characterization urgent and relevant in our context in order to assist the veterinary clinician, surgeon, and pathologist in establishing a precise diagnosis of these tumors.

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Published
2017-12-07
How to Cite
Leandro, R., Freitas, F., & Sá, L. R. (2017). The importance of clinical, histopathological and immunohistochemical marking for differential diagnosis of non-hematopoietic gastrointestinal mesenchymal neoplasms in dogs: literature review. Brazilian Journal of Veterinary Research and Animal Science, 54(4), 287-297. https://doi.org/10.11606/issn.1678-4456.bjvras.2017.128846