Hypothyroid associated polyneuropathy in dogs: Report of six cases

  • Adriana Patricia Suraniti University of Buenos Aires, Faculty of Veterinary Science, Buenos Aires, Argentina
  • Liliana Rosa Gilardoni University of Buenos Aires, Faculty of Veterinary Science, Buenos Aires, Argentina
  • Mabel Graciela Rama Llal University of Buenos Aires, Faculty of Veterinary Science, Buenos Aires, Argentina
  • Marcelo Echevarría University of Buenos Aires, Faculty of Veterinary Science, Buenos Aires, Argentina
  • Mary Marcondes Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Araçatuba, SP
Keywords: Thyroid hormones, Motor nerve conduction velocity, Neuropathy

Abstract

Six Doberman Pinscher, between six and eight years of age, were presented to the Veterinary Hospital from Faculty of Veterinary Science of The University of Buenos Aires. Neurological examination revealed tetraparesis with inability to walk, decreased muscle tonus and myotatic reflexes in all dogs. Serum cholesterol levels, creatine kinase and alkaline phosphatase activities were mildly to markedly elevated, and tibial motor nerve conduction velocities were slow in all dogs. Basal measurements of free T4 and TSH were determined by radioimmunoassay. Although fT4 values were within normal range, in all dogs TSH values were elevated. Based on this results, hypothyroidism was diagnosed and a supplementation therapy was established with oral levothyroxine (T4). Two weeks after treatment has been started, all patients had an improvement in clinical signs, and within a month gait became normal, as well as muscular tonus and spinal reflexes.

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Published
2008-08-01
How to Cite
Suraniti, A., Gilardoni, L., Llal, M., Echevarría, M., & Marcondes, M. (2008). Hypothyroid associated polyneuropathy in dogs: Report of six cases. Brazilian Journal of Veterinary Research and Animal Science, 45(4), 284-288. https://doi.org/10.11606/issn.1678-4456.bjvras.2008.26687
Section
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