Measurement of serum total thyroxine by chemiluminescence method in clinically healthy cats

  • Aline Bomfim Vieira Universidade Federal Fluminense, Faculdade de Medicina Veterinária, Departamento de Patologia e Clínica Veterinária, Niterói, RJ
  • Maria Cristina Nobre e Castro Universidade Federal Fluminense, Faculdade de Medicina Veterinária, Departamento de Patologia e Clínica Veterinária, Niterói, RJ
  • Isabel Maria Alexandre Freire Universidade Federal Fluminense, Faculdade de Medicina Veterinária, Departamento de Patologia e Clínica Veterinária, Niterói, RJ
  • Maysa Joppert Coelho Instituto Militar de Engenharia, Departamento de Estatística, Rio de Janeiro, RJ
  • Nayro Xavier de Alencar Universidade Federal Fluminense, Faculdade de Medicina Veterinária, Departamento de Patologia e Clínica Veterinária, Niterói, RJ
  • Ana Maria Barros Soares Universidade Federal Fluminense, Faculdade de Medicina Veterinária, Departamento de Patologia e Clínica Veterinária, Niterói, RJ
Keywords: Cats, Thyroid, Total thyroxine, Chemiluminescence

Abstract

Measurement of serum total thyroxine is the standard method to diagnose feline hyperthyroidism which is now considered the most common endocrine disease in cats. Factors as luminosity and temperature were incriminated as causes for thyroid hormones variation in dogs. The present study aimed to determine reference values for serum total thyroxine in healthy cats in Rio de Janeiro; to compare these findings with values from laboratories inside and outside Brazil and finally, to analyze the effect of gender and age on serum total thyroxine concentration. One hundred nineteen healthy cats, living in Rio de Janeiro for at least five months, from both sex and different breeds were used in this study. Serum thyroxine was measured on 119 samples by Chemiluminescent Enzyme Immunoassay (CEIA) method. Cats aged between five months and 18 years (7.11 ± 3.64). The lowest and highest serum T4 concentration founded in the whole population was 0.44 µg/dL and 4.6 µg/dL respectively. The reference range for this population was 0.75 - 3.5 µg/dL. According to samples included in this study, there was no difference between males and females thyroxine values (α = 0.05). However, age significantly influenced T4 concentrations with a positive correlation (p < 0.05).

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Published
2010-06-01
How to Cite
Vieira, A., Castro, M., Freire, I., Coelho, M., Alencar, N., & Soares, A. (2010). Measurement of serum total thyroxine by chemiluminescence method in clinically healthy cats. Brazilian Journal of Veterinary Research and Animal Science, 47(3), 224-230. https://doi.org/10.11606/issn.1678-4456.bjvras.2010.26860
Section
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