Assessment of clinical and biochemical profile of cattle during induction and treatment of hypocalcemia

  • Raimundo Alves Barrêto Júnior Universidade Federal Rural do Semi-Árido, Mossoró, RN
  • Antonio Humberto Hamad Minervino Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Frederico Augusto Mazzocca Lopes Rodrigues Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Enoch Brandão de Souza Meira Júnior Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Rodrigo N. F. Ferreira Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Alessandra Silva Lima Vallée, São Paulo, SP
  • Clara Satsuki Mori Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Isabela de Oliveira Barros Universidade Federal Rural do Semi-Árido, Mossoró, RN
  • Enrico Lippi Ortolani Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
Keywords: Calcium, Phosphorus, Treatment, Hypocalcaemia, EDTA

Abstract

The present work aims to study the clinical picture, biochemical profile and treatment response in cattle with induced hypocalcaemia. Were utilized 12 heifers randomly distributed in treated (n = 7) and control (n = 5) groups. The induction model was carried on by continuous EDTA infusion into jugular vein until the animals present clinical signs of hypocalcaemia. After that, the treated group received a calcium (Ca) solution enriched with phosphorus, magnesium and glucose with a dose of 1 mL/kg/BW in 30 minutes, meanwhile, the control group was treated with the same dose of physiologic solution. Clinical examination were performed and blood samples were obtained in times T0 (basal time), T1 (beginning of hypocalcaemia); T2 (end of EDTA infusion); T3 (end of treatment) and T4 (24 hours after the induction). All the heifers present temporary blood calcium and phosphorus reduction and demonstrated classical clinical picture of hypocalcaemia. The treated group present full clinical recovery and blood calcium and phosphorus increase. Most evident clinical signs were increasing heart beat, hypophonesis and rumenal atony. Those symptoms were reversed after calcium treatment. The solution used for treatment was efficient on clinical recovery within thirty minutes, promoting the return to basal levels of the most of biochemical's variables.

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Published
2011-06-01
How to Cite
Barrêto Júnior, R., Minervino, A., Rodrigues, F., Meira Júnior, E., Ferreira, R., Lima, A., Mori, C., Barros, I., & Ortolani, E. (2011). Assessment of clinical and biochemical profile of cattle during induction and treatment of hypocalcemia. Brazilian Journal of Veterinary Research and Animal Science, 48(3), 192-199. https://doi.org/10.11606/S1413-95962011000300002
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