Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells

  • Terezinha Regina Prúpere Ogata Instituto Butantã, Laboratório de Anatomia Patológica, São Paulo, SP
  • José Luiz Guerra Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Francisco Javier Hernandez Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos, Pirassununga, SP
Keywords: Extracellular matrix, KB cells, Histochemical, Nude rats

Abstract

A comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.

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Published
1997-08-01
How to Cite
Ogata, T. R., Guerra, J. L., & Hernandez, F. J. (1997). Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells. Brazilian Journal of Veterinary Research and Animal Science, 34(4), 203-206. https://doi.org/10.11606/issn.2318-3659.v34i4p203-206
Section
BASIC SCIENCES