Cellular exudation induced by carrageenan in the peritoneal cavity of chicks

Authors

  • Alda Maria Backx Noronha Madeira Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Nair Massako Katayama Ito Spave Consultoria, Estudo e Comércio em Produção e Saúde Animal Ltda., São Paulo, SP

DOI:

https://doi.org/10.11606/issn.2318-3659.v34i6p317-320

Keywords:

Carrageenan, Inflammation, Exudates, Cell counting, Hens

Abstract

The cellular response, induced by the carrageenan injection (4.5 ml; 0.2% w/v) in Ringer-Locke solution into the peritoneal cavity of chicks (three to six-week old Isa Brown males), was evaluated by total and differential inflammatory cell counting of exudates collected 0.5 to 4 hours after stimulus. An increased leucocyte exudation, with predominance of heterophils, was
observed within 1 and 4 hours post-stimulus. Macrophages were the second predominant cell type, followed by lymphocytes, eosinophils and basophils, in decreasing order. Thrombocytes were not significant in the peritoneal inflammatory exudate. Results presented in this work indicate that the peritoneal cavity can be utilized as a good model for studying the acute
inflammatory response of chickens.

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Published

1997-12-01

How to Cite

Madeira, A. M. B. N., & Ito, N. M. K. (1997). Cellular exudation induced by carrageenan in the peritoneal cavity of chicks. Brazilian Journal of Veterinary Research and Animal Science, 34(6), 317-320. https://doi.org/10.11606/issn.2318-3659.v34i6p317-320

Issue

Section

BASIC SCIENCES