Equine leukoencephalomalacia: report of five cases

  • José Guilherme Xavier Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Carlos Henrique Maciel Brunner Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Monica Sakamoto Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Benedito Corrêa Universidade de São Paulo, Instituto de Ciências Biomédicas, São Paulo, SP
  • Wilson Roberto Fernandes Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • José Luiz Catão Dias Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
Keywords: Mycotoxi coses, Food contamination (moldy corn), Poisoning, Fusarium moniliforme, Encephalomalacia, Horses

Abstract

This paper reports the occurrence of 5 cases of Equine Leukoencephalomalacia associated with the ingestion of mouldy corn during the winter of 1990 in three properties of the State of São Paulo, in the municipal districts of Poá, Pirassununga and Santana do Parnaíba. The animals showed in every case the following clinical signs: blindness, ataxia, dysphagya, tendency to circle and convulsions. The necropsy revealed congestion of brain and areas of cavitation within the hemispheres of subcortical white matter. The histopathological examination show edlesions characterized by liquefactive necrosis, multifocal haemorrhages and cellular infiltration, predominantly of polimorphonuclear (neutrophils and eosinophils) associated with mononuclear cells in the white matter. Microbiological analysis showed a mycoflora composed, predominantly, by Fusarium moniliforme (49.4%), followed by genera Aspergillus (25.8%) and Penicillum (24.8%).

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Published
1991-12-02
How to Cite
Xavier, J. G., Brunner, C. H., Sakamoto, M., Corrêa, B., Fernandes, W. R., & Dias, J. L. (1991). Equine leukoencephalomalacia: report of five cases. Brazilian Journal of Veterinary Research and Animal Science, 28(2), 185-189. https://doi.org/10.11606/issn.1678-4456.bjvras.1991.51937
Section
ANIMAL PATHOLOGY