Use of intraocular acrylic resin prosthesis. Experimental study in rats

  • Sheila Canevese Rahal Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia e Anestesiologia Veterinárias, Botucatu, SP
  • Silvana Artioli Schellini Universidade Estadual Paulista, Faculdade de Medicina, Departamento de Oftalmologia e Otorrinolaringologia, Botucatu, SP
  • Mariângela Esther Alencar Marques Universidade Estadual Paulista, Faculdade de Medicina, Departamento de Patologia, Botucatu, SP
  • José Joaquim Titon Ranzani Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia e Anestesiologia Veterinárias, Botucatu, SP
Keywords: Prosthesis, Methylmethacrylate, Rats, Eye artificial

Abstract

The ocular globe was eviscerated in 32 Wistar rats, divided in four groups (A, B, C, D) of eight animals each. Acrylic resin prosthesis was implanted into the corneoscleral membrane in five animals of each group. The other three did not receive the prosthesis. The methylmetacrylate sphere was manufactured and autoclaved. The animals from A, B, C and D groups were euthanized at 7, 15, 30 and 90 days after surgery, in the same order, and the orbital content was submitted to histopathological examination. A granulomatous inflammatory response surrounded the prosthesis and inflammatory edema in the cornea was observed mainly in the animals of A and B groups. The volume of the anophthalmic cavity was replaced in all animals that received the prosthesis, but not in the animals that did not received it. It was concluded that intraocular prosthesis of acrylic resin is a cosmetic alternative for correction of the defect produced by the lost of the ocular globe.

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Published
2000-01-01
How to Cite
Rahal, S., Schellini, S., Marques, M., & Ranzani, J. (2000). Use of intraocular acrylic resin prosthesis. Experimental study in rats. Brazilian Journal of Veterinary Research and Animal Science, 37(4), 286-290. https://doi.org/10.1590/S1413-95962000000400004
Section
BASIC SCIENCES