Phytochemical evaluation and wound healing potential of the fruit extract ethanolic of Jucá (Libidibia ferrea) in Wistar rats

  • Yuri Teiichi da Silva Kobayashi Universidade Federal do Pará
  • Vívian Tavares de Almeida Universidade Federal do Pará
  • Talita Bandeira Universidade Federal do Pará
  • Bianca Nascimento de Alcântara Universidade Federal do Pará
  • Andressa Santa Brígida da Silva Universidade Federal do Pará
  • Wagner Luiz Ramos Barbosa Universidade Federal do Pará
  • Paula Barbosa da Silva Universidade Federal do Pará
  • Maria Vivina Barros Monteiro Universidade Federal do Pará
  • Milton Begeres de Almeida Universidade Federal do Pará
Keywords: Skin, Healing, Plant drug

Abstract

Libidibia ferrea is a plant popularly used for therapeutic purposes, including processes to accelerate wound healing. The present investigation analyzed the chemical composition and the healing potential of ethanolic extract of the fruits of L. ferrea (Mart. ex Tul.) in rats. This study used 24 Wistar rats divided into four groups. In all animals a piece of skin on the back was removed and each group received a different treatment: NaCl 0.9%, Chlorhexidine digluconate 1%, ethanol extract of the fruits of Libidibia ferrea 12.5% and 50%. The healing process was evaluated macroscopically and microscopically. The ethanolic extract of the fruits of L. ferrea 12.5% was significantly more efficient than the 50% healing in rat skin.

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Published
2015-04-13
How to Cite
Kobayashi, Y., Almeida, V., Bandeira, T., Alcântara, B., Silva, A., Barbosa, W. L., Silva, P., Monteiro, M., & Almeida, M. (2015). Phytochemical evaluation and wound healing potential of the fruit extract ethanolic of Jucá (Libidibia ferrea) in Wistar rats. Brazilian Journal of Veterinary Research and Animal Science, 52(1), 34-40. https://doi.org/10.11606/issn.1678-4456.v52i1p34-40
Section
ARTICLES