Serum protein concentration in newborn calves fed with colostrum from cows with mastitis

  • Guilherme Gonçalves Fabretti Santos Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Programa de Ciência Animal, Araçatuba, SP
  • Maurício Deschk Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Programa de Ciência Animal, Araçatuba, SP
  • André Kielius Guedes Silva Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Araçatuba, SP
  • Tatiane Silva Pólo Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Programa de Ciência Animal, Araçatuba, SP
  • Márcia Marinho Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Departamento de Apoio da Produção e Saúde Animal, Araçatuba, SP
  • Juliana Regina Peiró Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Departamento de Clínica, Cirurgia e Reprodução Animal, Araçatuba, SP
  • Luiz Cláudio Nogueira Mendes Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Departamento de Clínica, Cirurgia e Reprodução Animal, Araçatuba, SP
  • Francisco Leydson Formiga Feitosa Universidade Estadual Paulista, Faculdade de Medicina Veterinária, Departamento de Clínica, Cirurgia e Reprodução Animal, Araçatuba, SP
Keywords: Passive transfer immunity, Colostrum, Mastitis, Immunoglobulins

Abstract

The aim of this study was to evaluate the serum protein concentration in newborns fed with colostrum derived from healthy cows (n = 10), cows with subclinical mastitis (n = 10) and cows with clinical mastitis (n = 10). 30 Holstein cows were assigned to their respective groups according to macroscopic examination of colostral secretion, somatic cell count, CMT and presence of bacteria in colostrum samples. Blood samples of the calves were collected immediately after birth, at 24 and 48 hours after ingestion of colostrum. The total protein was measured by the biuret method and the concentrations of immunoglobulin A (IgA), immunoglobulin G (IgG), transferrin, albumin and haptoglobin was determined by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). No differences were observed amongst groups in the concentrations of albumin, total protein and IgA. In animals from cows with subclinical and clinical mastitis haptoglobin concentrations were higher than those of healthy animals. The concentrations of IgG and transferrin were significantly lower in calves from cows with mastitis. We concluded that the ingestion of colostrum from infected and uninfected glands from cows with mastitis (GII e GIII) is unlikely to be an important contributor to the high rate of failure of passive transfer of immunoglobulins in calves.

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Published
2013-06-21
How to Cite
Santos, G., Deschk, M., Silva, A., Pólo, T., Marinho, M., Peiró, J. R., Mendes, L. C., & Feitosa, F. (2013). Serum protein concentration in newborn calves fed with colostrum from cows with mastitis. Brazilian Journal of Veterinary Research and Animal Science, 50(3), 188-197. https://doi.org/10.11606/issn.1678-4456.v50i3p188-197
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