Genome association analysis for pregnancy status following parturition in crossbred beef cattle

  • Juliano Coelho da Silveira Universidade Luterana do Brasil, Hospital Veterinário, Laboratório de Biotecnologia, Canoas, RS
  • Daniel Thompsen Passos Universidade Luterana do Brasil, Hospital Veterinário, Laboratório de Biotecnologia, Canoas, RS
  • Werner Giehl Glanzner Universidade Federal de Santa Maria, Laboratório de Biotecnologia e Reprodução Animal, Santa Maria, RS
  • Paulo Ricardo Loss Aguiar Universidade Luterana do Brasil, Hospital Veterinário, Laboratório de Biotecnologia, Canoas, RS
  • José Carlos Ferrugem Moraes Embrapa Pecuária Sul, Bagé, RS
  • Tania de Azevedo Weimer Universidade Luterana do Brasil, Hospital Veterinário, Laboratório de Biotecnologia, Canoas, RS
Keywords: Bovine, Marked-assisted selection, Reproductive performance, Short tandem repeats, Single nucleotide polymorphisms

Abstract

The aim of this study was to evaluate genetic diversity of nine molecular markers, six short tandem repeats - STRs (BM4325, BMS3004, ILSTS002, IDVGA51, HEL5, AFZ1) and three single nucleotide polymorphisms (SNPs; LepSau3A1 A-B, LepSau3A1 1-2, and FSHRAlu1), linked to genes involved in reproductive function and their possible effect on reproductive performance. For this purpose, 81 crossbred beef cows were used in this study. The animals were classified into two groups (fertile and sub-fertile cows) based on their pregnancy status after two breeding seasons. High genetic diversity level was observed highlighted by the polymorphic content information ranging 0.23 to 0.87 and expected heterozygosity from 27 to 89%, with an average of 62%. Alleles BM4325 103, BMS3004 129, ILSTS002 137, IDVGA51 177, LEPSau3A1 A, LEPSau3A1 1, HEL5 149, AFZ1 119 and FSHRAlu1 G presented high frequencies. Two STRs (IDVGA51 and ILSTS002), linked to Leptin and LHβ genes, respectively, were associated to reproductive performance. These data support previous findings suggesting the potential use of IDVGA51 and ILSTS002 STRs for reproductive performance selection.

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Published
2013-10-29
How to Cite
Silveira, J., Passos, D., Glanzner, W., Aguiar, P. R., Moraes, J. C., & Weimer, T. de. (2013). Genome association analysis for pregnancy status following parturition in crossbred beef cattle. Brazilian Journal of Veterinary Research and Animal Science, 50(5), 406-413. https://doi.org/10.11606/issn.2318-3659.v50i5p406-413
Section
ARTICLES