Peculiar clinical presentation of primary syphilis in the oral cavity

Authors

  • Jefferson da Rocha Tenório Universidade de São Paulo
  • Letícia Drumond de Abreu Guimarães Universidade de São Paulo
  • Bruno Fernandes Matuck Universidade de São Paulo
  • Thalita Santana Conceição Universidade de São Paulo
  • Matheus Sampaio de Oliveira Universidade Federal de Juiz de Fora
  • Suzane Cantanhede Orsini Machado de Sousa Universidade de São Paulo

DOI:

https://doi.org/10.11606/issn.2357-8041.clrd.2019.150981

Keywords:

Syphilis, Infection, Treponemal Infections

Abstract

Syphilis, a sexually transmitted infection, has increased in incidence over the years, especially among the adult popu­lation. The oral manifestation of primary syphilis is usually characterized by a clinical course variable in which it pro­gresses to the next stages if not treated. In this report, we present two cases of oral manifestation of primary syphilitic lesion with peculiar clinical characteristics, and we emphasize the importance of a correct diagnosis. Biopsies were needed for differential diagnosis and serological exams were requested. The histopathological analysis suggested the diagnosis and the immunohistochemistry confirmed the presence of Treponema pallidum. Antibiotic therapy was ini­tiated with complete remission of the lesion. Therefore, a thorough anamnesis and a thorough clinical examination are essential for establishing the correct diagnosis, to begin the treatment of syphilis as soon as possible, thus avoiding the disease’s progression.

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Author Biographies

Jefferson da Rocha Tenório, Universidade de São Paulo

Oral Pathology Department, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

Letícia Drumond de Abreu Guimarães, Universidade de São Paulo

Oral Pathology Department, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

Bruno Fernandes Matuck, Universidade de São Paulo

Oral Pathology Department, University of São Paulo, São Paulo, SP, Brazil

Thalita Santana Conceição, Universidade de São Paulo

Oral Pathology Department, University of São Paulo, São Paulo, SP, Brazil

Matheus Sampaio de Oliveira, Universidade Federal de Juiz de Fora

Dental Clinic Department, University of Juiz of Fora, Minas Gerais, MG, Brazil

Suzane Cantanhede Orsini Machado de Sousa, Universidade de São Paulo

Oral Pathology Department, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

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Published

2019-03-13

Issue

Section

Case report or technical report