Xerostomia in the older adult population, from diagnosis to treatment
a literature review
DOI:
https://doi.org/10.11606/issn.2357-8041.clrd.2019.157759Keywords:
Xerostomia, Dry mouth, SalivaAbstract
Saliva is important for the preservation and maintenance of normal physiological conditions of oral tissues, and factors influencing its decrease are associated with the risk for oral diseases. Xerostomia is the subjective sensation of oral dryness, which can be influenced by etiological factors including the use of several types of medications, Sjogren’s and metabolic syndromes, head and neck irradiation, among others. Treatment methods for xerostomia vary and can be local or systemic. The aim of this article is to present the results of a literature review addressing the correlation between xerostomia and its incidence and prevalence in the older adult population. Results of this review highlight the importance of diagnosis and appropriate management, and briefly describe treatment modalities and etiological factors such as medications, Sjogren’s syndrome, metabolic syndrome, and head and neck irradiation.
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References
Abrantes JPM. A xerostomia no idoso [dissertação]. Porto: Universidade do Porto, 2014.
Turner MD, Ship JA. Dry mouth and its effects on the oral health of elderly people. J Am Dent Assoc. 2007;138 Suppl:15S-20S. doi: 10.14219/jada.archive.2007.0358.
Montenegro FLB, Pereira CMM, Marchini L, Nascimento DFF. Efeitos colaterais bucais dos medicamentos em idosos: um ponto muito importante para discussão pela equipe interdisciplinar de cuidados em saúde. Meeting de Função Oral do Idoso; 2004 Sep 2-4; Helsinki. Athens: ECG; 2004.
Feio M, Sapeta P. Xerostomia em cuidados paliativos. Acta. Med. Port. [Internet]. 2005 [cited 2019 Oct 17];18(6):459-66. Available from: http://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1064
Proctor GB, Carpenter GH. Salivary secretion: mechanism and neural regulation. Monogr Oral Sci. 2014;24:14-29. doi: 10.1159/000358781.
Hopcraft MS, Tan C. Xerostomia: an update for clinicians. Aust Dent J. 2010;55(3):238-44. doi: 10.1111/j.1834-7819.2010.01229.x.
Orellana MF, Lagravère MO, Boychuk DG, Major PW, Flores-Mir C. Prevalence of xerostomia in population-based samples: a systematic review. J Public Health Dent. 2006;66(2):152-8. doi: 10.1111/j.1752-7325.2006.tb02572.x.
Porter SR, Scully C, Hegarty AM. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97(1):28-46. doi: 10.1016/j.tripleo.2003.07.010.
Rosa LB, Zuccolotto MCC, Bataglion C, Coronatto EAS. Odontogeriatria – a saúde bucal na terceira idade. RFO UPF. 2008;13(2):82-6. doi: 10.5335/rfo.v13i2.599.
Koshy JM, John M, George P. Primary Sjögren syndrome. Natl Med J India. 2014;27(2):120.
Tremblay M, Brisson D, Gaudet D. Association between salivary pH and metabolic syndrome in women: a cross-sectional study. BMC Oral Health. 2012;12(1):40. doi: 10.1186/1472-6831-12-40.
Alexander C, Bader JB, Schaefer A, Finke C, Kirsch CM. Intermediate and long-term side effects of high-dose radioiodine therapy for thyroid carcinoma radioiodine treatment. J Nucl Med. 1998;39(9):1551-4.
Guggenheimer J, Moore PA. Xerostomia: etiology, recognition and treatment. J Am Dent Assoc. 2003;134(1):61-9. doi: 10.14219/jada.archive.2003.0018.
Pijpe J, Kalk WW, Bootsma H, Spijkervet FK, Kallenberg CG, Vissink A. Progression of salivary gland dysfunction in patients with Sjögren’s syndrome. Ann Rheum Dis. 2007;66(1):107-12. doi: 10.1136/ard.2006.052647.
Brosky ME. The role of saliva in oral health: strategies for prevention and management of xerostomia. J Support Oncol. 2007;5(5):215-25.
Côrte-Real IS, Figueiral MH, Campos JCR. As doencas orais no idoso – consideracões gerais. Rev. Port. Estomatol. Cir. Maxilofac. 2011;52(3):175-80. doi: 10.1016/j.rpemd.2011.05.002.
Rhodus NL, Bereuter J. Clinical evaluation of a commercially available oral moisturizer in relieving signs and symptoms of xerostomia in postirradiation head and neck cancer patients and patients with Sjogren’s syndrome. J Otolaryngol. 2000;29(1):28-34.
Silvestre FJ, Minguez MP, Suñe-Negre JM. Clinical evaluation of a new artificial saliva in spray form for patients with dry mouth. Med Oral Patol Oral Cir Bucal. 2009;14(1):E8-E11.
Christersson CE, Lindh L, Arnebrant T. Film-forming properties and viscosities of saliva substitutes and human whole saliva. Eur J Oral Sci. 2000;108(5):418-25.
Strietzel FP, Martín-Granizo R, Fedele S, Lo Russo L, Mignogna M, Reichart PA, et al. Electrostimulating device in the management of xerostomia. Oral Dis. 2007;13(2):206-13. doi: 10.1111/j.1601-0825.2006.01268.x.
Braga FPF. Avaliação da acupuntura como método de tratamento preventivo e curativo de xerostomia decorrente da radioterapia [dissertação]. São Paulo: Universidade de São Paulo; 2006. doi: 10.11606/D.23.2006.tde-05052006-164329.
Blom M, Dawidson I, Angmar-Månsson B. The effect of acupuncture on salivary flow rates in patients with xerostomia. Oral Surgery Oral Med Oral Pathol. 1992;73(3):293-8. doi: 10.1016/0030-4220(92)90124-9.
Blom M, Lundeberg T. Long‐term follow‐up of patients treated with acupuncture for xerostomia and the influence of additional treatment. Oral Dis. 2000;6(1):15-24.
Simões A, de Campos L, de Souza DN, de Matos JA, Freitas PM, Nicolau J. Laser phototherapy as topical prophylaxis against radiation-induced xerostomia. Photomed Laser Surg. 2010;28(3):357-63. doi: 10.1089/pho.2009.2486.
Lopes CO, Mas JRI, Zângaro RA. Prevenção da xerostomia e da mucosite oral induzidas por radioterapia com uso do laser de baixa potência. Radiol. Bras. 2006;39(2):131-6. doi: 10.1590/S0100-39842006000200012.
Delli K, Livas C, Spijkervet FK, Vissink A. Internet information on xerostomia: what should patients expect? Oral Dis. 2015;21(1):83-9. doi: 10.1111/odi.12213.
Lopes FF, Silva LFG, Carvalho FL, Oliveira AEF. Estudo sobre xerostomia, fluxo salivar e enfermidades sistêmicas em mulheres na pós-menopausa. Rev. Gauch. Odontol. 2008;56(2):127-30.
Dawes C. How much saliva is enough for avoidance of xerostomia? Caries Res. 2004;38(3):236-40. doi: 10.1159/000077760.
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