Genetics Bases of Cardiac Sodium Channel Mutations linked to Inherited Cardiac Arrhythmias

  • Hector Barajas-Martinez Molecular Genetics Department, Masonic Medical Research Laboratory, Utica, New York, USA
  • Dan Hu
  • Adrian Baranchuk

Resumo

Não se aplica

Referências

Pérez-Riera AR, Raimundo RD, Watanabe RA, Figueiredo JL, Abreu LC. The cardiac sodium channel its mutations and their spectrum arrhythmia phenotypes. J Hum Growth Dev. 2016; 26(3): 281-96. DOI: http://dx.doi.org/10.7322/jhgd.122759

Barajas-Martínez HM, Hu D, Cordeiro JM, Wu Y, Kovacs RJ, Meltser H, et al. Lidocaineinduced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel. Circ Res. 2008;103(4):396-404. DOI: http://dx.doi.org/10.1161/CIRCRESAHA.108.172619

Hu D, Barajas-Martinez H, Burashnikov E, Springer M, Wu Y, Varro A, et al. A mutation in the β3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype. Circ Cardiovasc Genet. 2009;2(3):270-8. DOI: http://dx.doi.org/10.1161/CIRCGENETICS.108.829192

Cordeiro JM, Barajas-Martinez H, Hong K, Burashnikov E, Pfeiffer R, Orsino AM, et al. Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome. Circulation. 2006; 114(19): 2026-33. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.106.627489

Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, et al. Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovasc Res. 2005;67(3):510-9. DOI: http://dx.doi.org/10.1016/j.cardiores.2005.03.024

Moreau A, Keller DI., Huang H, Fressart V, Schmied C, Timour Q, et al. Mexiletin differentially restores the traffi cking defects caused by two Brugada syndrome mutations Front Pharmacol. 2012;3:62. DOI: http://dx.doi.org/10.3389/fphar.2012.00062

Publicado
2016-11-28
Seção
Editorial