Fingernails as a biomarker for dental fluorosis

  • Lilian Rigo Professor, Department of Dentistry, Faculdade Meridional / IMED, Passo Fundo (RS)
  • Graziela Oro Cericato Professor, Department of Dentistry, Faculdade Meridional / IMED, Passo Fundo (RS)
  • Clarice Sagin Sabadin Professor, Department of Dentistry, Faculdade Meridional / IMED, Passo Fundo (RS)
  • Caroline Solda Lutheran University of Brazil, Canoas (RS),
  • Débora Nunes Mário Professor, Department of Dentistry, Faculdade Meridional / IMED, Passo Fundo (RS)
  • Marília Afonso Rabelo Buzalaf Professor, Department of Dentistry, School of Dentistry of Bauru (FOB/ Bauru), Bauru (SP)
Palavras-chave: Fluoride poisoning, Fluoride, Biological marker, Dental tooth fluorosis

Resumo

Introduction: Biomarkers indicate levels of a particular chemical agent in the environment studied, which may be useful for monitoring health status, and nails may be major indicators of fluoride.

Objective: To evaluate fluoride concentration in the fingernails of children as a biomarker for fluoride exposure.

Methods: Twenty students were selected, aged 4-5 years old. Their nails were cut at 15 and 45 days (two collections), and the fluoride concentration in the nails was analyzed with the ion-specific electrode (Orion 9409) after rapid diffusion with HDMS.

Results: The total fluoride mean of the samples was 3.68 μg F/g (sd 1.44), ranging from 1.39 μg F/g to 7.81 μg F/g. Eleven children (55%) brush their teeth three times a day, but only three children (15%) swallow toothpaste.

Conclusion: There is a high prevalence of fluoride exposure in the fingernails of the children studied, presenting risk of developing dental fluorosis in permanent teeth.


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Publicado
2018-03-12
Seção
Artigos Originais