HPV vaccine: knowledge and acceptance to ensure effectiveness

  • Isabel Cristina Esposito Sorpreso Disciplina de Ginecologia. Departamento de Obstetrícia e Ginecologia da Faculdade de Medicina da Universidade de São Paulo
  • Patricia Jane Kelly School of Nursing. University of Missouri
Palavras-chave: HPV, papillomavirus vaccines, human papillomavirus recombinant vaccine quadrivalent, types 6, 11, 16, 18, uterine cervical neoplasms


The new Vaccine technologies against transmissible and non-transmissible diseases, such as cancer, have had an impact on international public health. The human papillomavirus (HPV) vaccine is used on a large scale in immunization programs in more than 58 countries, with resultant efficacy and safety for precursor lesions of cervical cancer, in addition to anogenital lesions. After the introduction of quadrivalent HPV vaccine (6,11,16 and 18) in Brazil in 2014, monitoring the vaccination coverage and the development of HPV prevalence incidence of cervical abnormalities and precancerous lesions must be observed, as well as morbidity and mortality trends from in situ and invasive cancer. Encouraging information, counseling and continuing education is recommended as a strategy to broaden vaccine acceptance in order to sediment its implementation and ensure effectiveness in reducing new cases of cervical cancer in the future.


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