Prostate carcinoma with neuroendocrine differentiation: case report and literature review
Keywords:Prostatic carcinoma, Neuroendocrine differentiation, Autopsy, Immunohistochemistry, Splenic metastasis
AbstractNeuroendocrine differentiation in prostatic carcinomas generally confers a more aggressive clinical behavior and less favorable prognosis than usual prostatic carcinomas. In this manuscript, we report a case of a 58-year-old man with prostatic carcinoma who died 1 year after initial diagnosis. Autopsy showed a disseminated prostatic carcinoma with neuroendocrine differentiation. There were metastasis to the spleen, an organ infrequently involved by disseminated epithelial neoplasms. Neuroendocrine differentiation was demonstrated by immunohistochemical studies in the biopsy and autopsy material.
How to Cite
Fernandes, R. C. M., Matsushita, M. de M., Mauad, T., & Saldiva, P. H. N. (2001). Prostate carcinoma with neuroendocrine differentiation: case report and literature review . Revista Do Hospital Das Clínicas, 56(5), 153-158. https://doi.org/10.1590/S0041-87812001000500005