ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS

  • Eduardo José J. MALLMANN Universidade Federal do Ceará; Departamento de Química Analítica e Físico-Química; Grupo de Química de Materiais Avançados; Universidade Federal do Ceará
  • Francisco Afrânio CUNHA Universidade Federal do Ceará; Departamento de Análises Clínicas e Toxicológicas; Laboratório de Microbiologia de Leveduras; Universidade Federal do Ceará
  • Bruno N.M.F. CASTRO Universidade Federal do Ceará; Departamento de Análises Clínicas e Toxicológicas; Laboratório de Microbiologia de Leveduras; Universidade Federal do Ceará
  • Auberson Martins MACIEL Universidade Federal do Ceará; Departamento de Análises Clínicas e Toxicológicas; Laboratório de Microbiologia de Leveduras; Universidade Federal do Ceará
  • Everardo Albuquerque MENEZES Universidade Federal do Ceará; Departamento de Análises Clínicas e Toxicológicas; Laboratório de Microbiologia de Leveduras; Universidade Federal do Ceará
  • Pierre Basílio Almeida FECHINE Universidade Federal do Ceará; Departamento de Química Analítica e Físico-Química; Grupo de Química de Materiais Avançados; Universidade Federal do Ceará

Abstract

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.

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Published
2015-04-01
How to Cite
MALLMANN, E., CUNHA, F., CASTRO, B., MACIEL, A., MENEZES, E., & FECHINE, P. (2015). ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS . Revista Do Instituto De Medicina Tropical De São Paulo, 57(2), 165-167. Retrieved from http://www.revistas.usp.br/rimtsp/article/view/100972
Section
Brief Communications