Prevalence of schistosomiasis mansoni in indigenous Maxakali villages, Minas Gerais, Brazil

Authors

  • Maria Beatriz Pena e Silva Leite Nacife Universidade Federal de Ouro Preto; Núcleo de Pesquisa em Ciências Biológicas; Programa de Pós-Graduação em Ciências Biológicas
  • Liliane Maria Vidal Siqueira Fundação Oswaldo Cruz; Instituto de Pesquisas René Rachou; Laboratório de Esquistossomose
  • Rafael Martins Universidade Federal de Ouro Preto; Núcleo de Pesquisa em Ciências Biológicas; Programa de Pós-Graduação em Ciências Biológicas
  • Valeska Natiely Vianna Universidade Federal de Ouro Preto; Escola de Medicina; Laboratório de Epidemiologia
  • Keila Furbino Barbosa Universidade Federal de Ouro Preto; Pós-Graduação em Saúde e Nutrição
  • Cássio Zumerle Masioli Universidade Federal de Ouro Preto; Escola de Medicina; Laboratório de Epidemiologia
  • Jaime Costa da Silva Ministério da Saúde; Secretaria Especial de Saúde Indígena
  • George Luiz Lins Machado-Coelho Universidade Federal de Ouro Preto; Escola de Medicina; Laboratório de Epidemiologia

Keywords:

Schistosomiasis, Parasitological techniques, Helminthes, Indigenous populations, Prevalence

Abstract

Intestinal parasitic infections are a common health problem among Amerindian populations and schistosomiasis represents one of the most prevalent diseases in Maxakali people. The Kato-Katz is the diagnostic method recommended by WHO for epidemiological studies; however, one of the technique’s limitations is the failure to detect parasites in individuals with low parasite load. The aim of this study was to establish the prevalence of Schistosoma mansoni in indigenous Maxakali villages, evaluating the TF-Test® performance for diagnosis compared to the Kato-Katz technique. Stool samples from 545 individuals were processed by the TF-Test® (1 sample) and Kato-Katz (1 slide). The positivity rate for S. mansoni by Kato-Katz was 45.7%. The rate by the TF-Test® was 33.2%, and 51.9% by the combined parasitological techniques. The amplitude of parasite load was 24 to 4,056 eggs per gram of feces (epg), with a geometric mean of 139 epg. The co-positivity, co-negativity, and accuracy values by TF-Test® in relation to Kato-Katz were 59.0%, 88.5%, and 75.0%, respectively. The agreement between these techniques was moderate (k=0.486) as determined by the kappa index. Thus, the results of this study demonstrated that the performance of Kato-Katz was superior (p <0.05) to that of TF-Test® in the detection of S. mansoni. The combination of TF-Test® and Kato-Katz resulted in an increased positivity rate of S. mansoni, demonstrating the high risk of infection to which indigenous populations are exposed and the importance of the implementation of control strategies in Maxakali villages.

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Published

2018-01-01

Issue

Section

Original Articles

How to Cite

Prevalence of schistosomiasis mansoni in indigenous Maxakali villages, Minas Gerais, Brazil. (2018). Revista Do Instituto De Medicina Tropical De São Paulo, 60, e26. https://revistas.usp.br/rimtsp/article/view/148076