Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil

Authors

  • Regyane Ferreira Guimarães Dias Universidade Federal de Goiás
  • Luciana Oliveira Bento Universidade Federal de Goiás
  • Camila Tavares Universidade Federal de Goiás
  • Hélio Ranes Filho Universidade Federal de Goiás
  • Melisia Adelaide Cesário da Silva Secretaria Municipal de Saúde, Serviço de Assistência Especializada
  • Luciene Carneiro Moraes Secretaria Municipal de Saúde, Serviço de Assistência Especializada
  • Ana Amélia Freitas-Vilela Universidade Federal de Goiás
  • Marcos Lázaro Moreli Universidade Federal de Goiás
  • Ludimila Paula Vaz Cardoso Universidade Federal de Goiás

Keywords:

HIV/AIDS, Epidemiology, Midwest Brazil

Abstract

Knowledge about epidemiological distribution patterns of HIV infection in different geographic regions is relevant to understand the dynamics of the disease in Brazil. This study aims to characterize the epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, from 2005 to 2015. A standardized questionnaire was used to collect clinical-epidemiological, virological, and immunological data from the medical records of all HIV-infected patients (n=539) who were followed at the regional reference center of Jatai, Goias State, Brazil, from 2005 to 2015. We detected the prevalence of male patients and the heterosexual route of transmission, as well as an expressive number of young women infected with HIV. The HIV infection was more prevalent in reproductive ages (55.3%). Most patients presented clinical manifestations related to HIV infection at the time of diagnosis. Twenty-four patients presented coinfection with hepatitis C virus, syphilis, hepatitis B virus, leprosy or Chagas disease. Pneumonia caused by Pneumocystis jirovecii was the most common opportunistic infection, followed by neurotoxoplasmosis, tuberculosis, and neurocryptococcosis. Combined antiretroviral therapy improved CD4+ T-cell counts: the mean CD4+ T-cell counts after treatment was twice as high as those found at the first medical appointment; and highly active antiretroviral therapy promoted viral suppression in a significant number of patients. Considering the increasing distribution of HIV infection to the interior of Brazil, this descriptive study outlines the clinical-epidemiological characteristics of HIV infection in Southwestern Goias and contributes to develop local prevention strategies and public service plans.

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Published

2018-11-07

Issue

Section

Original Articles

How to Cite

Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil. (2018). Revista Do Instituto De Medicina Tropical De São Paulo, 60, e34. https://revistas.usp.br/rimtsp/article/view/151611