PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE

Authors

  • Luciana Farias da Costa de Avila Universidade Federal de Pelotas
  • Paula de Lima Telmo UFPEL; Center of Technology Development - Biotechnology
  • Lourdes Helena Rodrigues Martins Universidade Federal do Rio Grande; Parasitology Laboratory
  • Thais Aimee Glaeser Universidade Federal do Rio Grande; Parasitology Laboratory
  • Fabricio Rochedo Conceicao UFPEL; Center of Technology Development - Biotechnology
  • Fabio Pereira Leivas Leite Universidade Federal de Pelotas
  • Carlos James Scaini FURG

Abstract

SUMMARY In a previous study our group found that the probiotic Saccharomyces boulardii was capable of reducing the intensity of infection in mice with toxocariasis. In order to assess whether the mechanism involved would be a direct action of the probiotic on Toxocara canis larvae, this study was designed. Both probiotics were singly cultivated in plates containing RPMI 1640 medium and T. canis larvae. S. boulardii and B. cereus var. toyoi cultures presented 97.6% and 95.7% of larvae with positive motility, respectively, and absence of color by the dye trypan blue, not representing significant difference to the control group (p >; 0.05). We conclude that none of the probiotics showed in vitro effects on T. canis larvae and that the interaction with the intestinal mucosa is necessary for the development of the protective effect of S. boulardii.

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Published

2013-09-01

How to Cite

Avila, L. F. da C. de, Telmo, P. de L., Martins, L. H. R., Glaeser, T. A., Conceicao, F. R., Leite, F. P. L., & Scaini, C. J. (2013). PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE . Revista Do Instituto De Medicina Tropical De São Paulo, 55(5), 363-365. Retrieved from http://www.revistas.usp.br/rimtsp/article/view/78672

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Section

Brief Communication