SEROLOGIC SURVEY ON HANTAVIRUS IN BLOOD DONORS FROM THE STATE OF SANTA CATARINA, BRAZIL

Authors

  • Caio Maurício Mendes de Cordova Universidade de Blumenau; Depto. de Ciências Farmacêuticas
  • Luiz Tadeu Moraes Figueiredo Universidade de São Paulo; Faculdade de Medicina; Centro de Pesquisa em Virologia. Ribeirão Preto

Abstract

Emergent diseases such as Hantavirus Cardio-pulmonary Syndrome (HCPS) are able to create a significant impact on human populations due to their seriousness and high fatality rate. Santa Catarina, located in the South of Brazil, is the leading state for HCPS with 267 reported cases from 1999 to 2011. We present here a serological survey on hantavirus in blood donors from different cities of the state of Santa Catarina, with an IgG-ELISA using a recombinant nucleocapsid protein from Araraquara hantavirus as an antigen. In total, 314 donors from blood banks participated in the study, geographically covering the whole state. Among these, 14 individuals (4.4%) had antibodies to hantavirus: four of 50 (8% positivity) from Blumenau, four of 52 (7.6%) from Joinville, three of 50 (6%) from Florianópolis, two of 50 (4%) from Chapecó and one of 35 (2.8%) from Joaçaba. It is possible that hantaviruses are circulating across almost the whole state, with important epidemiological implications. Considering that the seropositive blood donors are healthy individuals, it is possible that hantaviruses may be causing unrecognized infections, which are either asymptomatic or clinically nonspecific, in addition to HCPS. It is also possible that more than one hantavirus type could be circulating in this region, causing mostly benign infections.

Downloads

Download data is not yet available.

Downloads

Published

2014-07-01

Issue

Section

Virology

How to Cite

Cordova, C. M. M. de, & Figueiredo, L. T. M. (2014). SEROLOGIC SURVEY ON HANTAVIRUS IN BLOOD DONORS FROM THE STATE OF SANTA CATARINA, BRAZIL . Revista Do Instituto De Medicina Tropical De São Paulo, 56(4), 277-279. https://revistas.usp.br/rimtsp/article/view/84421