Metabolic syndrome in bipolar disorder

prevalence, demographics and clinical correlates in individuals with bipolar I, bipolar II, and healthy controls

  • Hanife Kocakaya Tokat Dr. Cevdet Aykan Mental Health Hospital
  • Sedat Batmaz Gaziosmanpasa University School of Medicine, Department of Psychiatry
  • Osman Demir Gaziosmanpasa University School of Medicine, Department of Statistics
  • Emrah Songur Ankara Kecioren Training and Research Hospital
  • Zekiye Celikbas Tokat Dr. Cevdet Aykan Mental Health Hospital
Keywords: Bipolar disorder I and II, metabolic syndrome, prevalence

Abstract

Background: The metabolic syndrome is a growing global public health problem and highly prevalent in patiens with bipolar disorder. There are a few studies about relationship between metabolic syndrome and bipolar disorder subtypes. Objective: The aim of this study was to investigate the prevalence of metabolic syndrome (MS) and its individual components in subjects with bipolar I (BD I) and bipolar II (BD II) disorder compared with non-psychiatric controls, and to determine the variables affecting MS. Methods: A total of 210 individuals (mean age 42.5 ± 11.87, 58.1% female) of whom 70 had BD I, 70 BD II, and 70 controls, were included in this study. MS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), the adapted ATP III (ATP III-A) and the International Diabetes Federation (IDF) criteria. Results: Participants with BD I had a significantly higher prevalence of MS when compared to individuals BD II and non-psychiatric controls according to the NCEP-ATP III, ATP III-A, and IDF criteria (ps < 0.01). In individuals with MS, increased waist circumference was the most common abnormality. Logistic regression analysis revealed that the presence of physical illness, age and number of cigarettes smoked significantly predicted the presence of MS. Discussion: This study showed that MS was more prevalent among BD I individuals compared to BD II and controls, and highlighted the importance of regular screening for MS in individuals with BD.

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Published
2018-12-19
How to Cite
Kocakaya, H., Batmaz, S., Demir, O., Songur, E., & Celikbas, Z. (2018). Metabolic syndrome in bipolar disorder. Archives of Clinical Psychiatry, 45(6), 143-149. https://doi.org/10.1590/acp.v45i6.153012
Section
Original Articles