Toxina botulínica tipo A: propriedades farmacológicas e uso clínico

Autores

  • Maria Matilde de Mello Sposito Universidade de São Paulo. Faculdade de Medicina

DOI:

https://doi.org/10.11606/issn.2317-0190.v11iSupl.1a102495

Palavras-chave:

Toxina Botulínica Tipo A

Resumo

Todas as informações contidas neste trabalho de revisão são referentes a toxina botulínica do tipo A (TBA) produzida por Allergan Inc, representada no Brasil por Allergan Produtos Farmacêuticos, cujo nome comercial é BOTOX®. A toxina botulínica do tipo-A é um agente biológico obtido laboratorialmente, sendo uma substância cristalina estável, liofilizada em albumina humana e apresentada em frasco a vácuo estéril, para ser diluída em solução salina. A TBA é produzida naturalmente pelo Clostridium botulinum, uma bactéria anaeróbia, que produz oito tipos sorológicos de toxina, sendo a do tipo-A a mais potente e por isto utilizada clinicamente.

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2004-12-14

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1.
Sposito MM de M. Toxina botulínica tipo A: propriedades farmacológicas e uso clínico. Acta Fisiátr. [Internet]. 14º de dezembro de 2004 [citado 17º de abril de 2024];11(Supl.1):S7-S44. Disponível em: https://www.revistas.usp.br/actafisiatrica/article/view/102495