Aretaeus of Cappadocia (1st century CE) described
a young man with chronic and recurring abdominal
distress possibly representing the first recorded instance
of Crohn disease (CD).1-3 More evidence that this disease
was extant for many years comes from the description
of the 10th century English king, Alfred “the great,”
who suffered for many years from what was a typical
enteritis but also had anal fistula and/or abscess.
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