Sudden death in infective endocarditis

Authors

  • Jussara Bianchi Castelli Universidade de São Paulo. Faculty of Medicine. Instituto do Coração. Anatomic Pathology Department
  • Germana Almeida Universidade de São Paulo. Faculty of Medicine. Instituto do Coração. Internal Medicine Department
  • Rinaldo Focaccia Siciliano Universidade de São Paulo. Faculty of Medicine. Instituto do Coração. Infectious Disease Control Department

DOI:

https://doi.org/10.4322/acr.2016.045

Keywords:

Lupus Erythematosus, Systemic, Endocarditis, Heart Arrest, Embolism, Coronary Vessels

Abstract

The case fatality rate of infective endocarditis (IE) is high and is associated with varying causes. Among them, acute myocardial infarction due to an embolism in a coronary artery is rare; the incidence of this complication in the setting of IE is reported to be up to 1.5%. We report a case of sudden death in a 22-year-old woman diagnosed with systemic lupus erythematosus who was referred to the Cardiology Center for the treatment of mitral valve incompetence due to IE. She was hemodynamically stable with antibiotic therapy and vasoactive drugs, despite severe mitral valve regurgitation. Unexpectedly, she presented cardiac arrest and died. The autopsy showed total occlusion of the left main coronary artery by septic embolus, which originated from the mitral vegetation, as the cause of death. Thus, although a rare complication, it should always be kept in mind that a coronary embolism can be a lethal complication of IE, and the possibility of surgical treatment combined with the underlying antibiotic therapy should be raised

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Published

2016-09-11

How to Cite

Castelli, J. B., Almeida, G., & Siciliano, R. F. (2016). Sudden death in infective endocarditis. Autopsy and Case Reports, 6(3), 17-22. https://doi.org/10.4322/acr.2016.045

Issue

Section

Article / Autopsy Case Report