Malignant ameloblastoma

a challenging diagnosis


  • Ayodeji Salamia Department of Pathology, University of Ibadan
  • Uchenna Ezenkwa Department of Pathology, University College Hospital
  • Mudashiru Salami Department of Cardiothoracic Surgery, University of Ibadan
  • Mustapha Ajani Department of Pathology, Babcock University
  • Clement Okolo Department of Pathology, University of Ibadan


Ameloblastoma, Mediastinum, Neoplasm Metastasis, Pulmonary Atelectasis


Ameloblastoma is an uncommon and locally aggressive, benign, odontogenic tumor, with local recurrence when not adequately excised. A rare variant of this neoplasm with the benign features but accompanied with metastases has been described. This rare variant is malignant ameloblastoma and is known to have a poor prognosis. We present the case of a young woman who had recurrent mandibular tumors, which were resected twice and histologically reported as ameloblastoma. Four years later, she presented with pulmonary metastasis and atelectasis. A review of the literature on this very rare neoplasm was also performed.


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How to Cite

Salamia, A., Ezenkwa, U., Salami, M., Ajani, M., & Okolo, C. (2018). Malignant ameloblastoma: a challenging diagnosis. Autopsy and Case Reports, 8(4), e2018043. Retrieved from



Article / Autopsy Case Report