Plasma cell cheilitis

the diagnosis of a disorder mimicking lip cancer

Authors

  • Harim Tavares dos Santos Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-6591-6808
  • John Lennon Silva Cunha Tiradentes University, Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research https://orcid.org/0000-0001-7404-7280
  • Lucas Alves Mota Santana Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-8261-1504
  • Cleverson Luciano Trento Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-1079-4217
  • Antônio Carlos Marquetti Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0001-5741-8668
  • Ricardo Luiz Cavalcanti de Albuquerque-Júnior Tiradentes University, Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research
  • Sílvia Ferreira de Sousa Federal University of Minas Gerais, Oral Surgery and Pathology Department, School of Dentistry

Keywords:

Cheilitis, Lip, Lip diseases, Plasma cell

Abstract

Plasma cell cheilitis (PCC) is an inflammatory disorder of unknown etiology that affects the lip. It is characterized histologically by a dense infiltrate of plasma cells with a variety of clinical features. The response to different therapeutic modalities is controversial, especially regarding the effectiveness of corticosteroids. We present a case of a 56-year-old Caucasian man with a painful ulcerated and crusted area in the lower lip, resembling a squamous cell carcinoma or actinic cheilitis. Topical corticosteroid was used for one week, which resulted in partial regression and motivated a biopsy. The histological examination provided the diagnosis of PCC. The patient has been disease-free for six months. We also provide a discussion on the criteria of differential diagnosis and management of this rare condition. See ERRATUM 

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Published

2019-04-12

How to Cite

Santos, H. T. dos, Cunha, J. L. S., Santana, L. A. M., Trento, C. L., Marquetti, A. C., Albuquerque-Júnior, R. L. C. de, & Sousa, S. F. de. (2019). Plasma cell cheilitis: the diagnosis of a disorder mimicking lip cancer. Autopsy and Case Reports, 9(2), e2018075. Retrieved from https://www.revistas.usp.br/autopsy/article/view/156808

Issue

Section

Article / Clinical Case Report