Plasma cell cheilitis

the diagnosis of a disorder mimicking lip cancer

Authors

  • Harim Tavares dos Santos Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-6591-6808
  • John Lennon Silva Cunha Tiradentes University, Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research https://orcid.org/0000-0001-7404-7280
  • Lucas Alves Mota Santana Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-8261-1504
  • Cleverson Luciano Trento Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0002-1079-4217
  • Antônio Carlos Marquetti Federal University of Sergipe, Department of Dentistry, Biological Sciences and Health Center https://orcid.org/0000-0001-5741-8668
  • Ricardo Luiz Cavalcanti de Albuquerque-Júnior Tiradentes University, Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research
  • Sílvia Ferreira de Sousa Federal University of Minas Gerais, Oral Surgery and Pathology Department, School of Dentistry

Keywords:

Cheilitis, Lip, Lip diseases, Plasma cell

Abstract

Plasma cell cheilitis (PCC) is an inflammatory disorder of unknown etiology that affects the lip. It is characterized histologically by a dense infiltrate of plasma cells with a variety of clinical features. The response to different therapeutic modalities is controversial, especially regarding the effectiveness of corticosteroids. We present a case of a 56-year-old Caucasian man with a painful ulcerated and crusted area in the lower lip, resembling a squamous cell carcinoma or actinic cheilitis. Topical corticosteroid was used for one week, which resulted in partial regression and motivated a biopsy. The histological examination provided the diagnosis of PCC. The patient has been disease-free for six months. We also provide a discussion on the criteria of differential diagnosis and management of this rare condition. See ERRATUM 

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Published

2019-04-12

Issue

Vol. 9 No. 2 (2019)

Section

Article / Clinical Case Report

License

Authors of articles published by Autopsy and Case Report retain the copyright of their work without restrictions, licensing it under the Creative Commons Attribution License - CC-BY, which allows articles to be re-used and re-distributed without restriction, as long as the original work is correctly cited.

How to Cite

Santos, H. T. dos, Cunha, J. L. S., Santana, L. A. M., Trento, C. L., Marquetti, A. C., Albuquerque-Júnior, R. L. C. de, & Sousa, S. F. de. (2019). Plasma cell cheilitis: the diagnosis of a disorder mimicking lip cancer. Autopsy and Case Reports, 9(2), e2018075. https://www.revistas.usp.br/autopsy/article/view/156808