Primary colonic liposarcomatosis: report of a case with review of literature

Authors

  • Mahesh Sultania All India Institute of Medical Sciences, Department of Surgical Oncology
  • Dillip Muduly All India Institute of Medical Sciences, Department of Surgical Oncology
  • Shilpy Jha All India Institute of Medical Sciences, Department of Pathology and Laboratory Medicine
  • Madhabananda Kar All India Institute of Medical Sciences, Department of Surgical Oncology
  • Suvradeep Mitra All India Institute of Medical Sciences, Department of Pathology and Laboratory Medicine

DOI:

https://doi.org/10.4322/acr.2018.056

Keywords:

Liposarcoma, Colonic Neoplasms, Proto-Oncogene Proteins c-mdm2

Abstract

LiposarcomaThe colon is a rare site of occurrence of liposarcoma, as either the primary site or by secondary involvement from a retroperitoneal liposarcoma. Liposarcomatosis denotes simultaneous occurrence of multiple liposarcomas. There are only 17 cases of primary colonic liposarcoma reported in the English literature—one of which was primary colonic liposarcomatosis. We depict the second case of primary colonic liposarcomatosis in a 57-year-old female who presented with abdominal swelling and pain. On exploratory laparotomy, two large masses were seen arising from the wall of the right colon along with multiple smaller masses attached to the colon. Right hemicolectomy with en bloc excision of the masses was performed along with hysterectomy and pelvic floor repair. Macroscopically, multiple exophytic masses and one endophytic mass were identified. The exophytic masses were of variable size and were found to hang from the colon by a thin pedicle simulating variable-sized appendices epiploicae. Histopathologically, the lesions showed the morphology of well-differentiated liposarcoma. This appears to be a case of primary colonic liposarcomatosis. There is only one other similar case reported in the English literature, to the best of our knowledge.

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Published

2019-08-14

How to Cite

Sultania, M., Muduly, D., Jha, S., Kar, M., & Mitra, S. (2019). Primary colonic liposarcomatosis: report of a case with review of literature. Autopsy and Case Reports, 9(1), e2018056. https://doi.org/10.4322/acr.2018.056

Issue

Section

Article / Clinical Case Report