Sudden onset acute liver failure in a patient with clinically occult small cell lung carcinoma: autopsy report and review of the medical literature

Authors

  • Massimiliano Guerriero A. Cardelli Regional Hospital, Regional Health Authority of Molise (ASReM), Department of Pathology https://orcid.org/0000-0002-7871-3655
  • Arnaldo Carbone Universita Cattolica del S. Cuore, Institute of Pathology https://orcid.org/0000-0001-9695-5837
  • Francesco Colasurdo Independent scholar
  • Valerio Pellegrini University of Molise, Department of Medicine and Health Sciences
  • Anna Maria Pollio A. Cardelli Regional Hospital, Regional Health Authority of Molise (ASReM), Department of Pathology

DOI:

https://doi.org/10.4322/acr.2019.089

Keywords:

Small Cell Lung Carcinoma, Hepatomegaly, Acute Liver Failure, Liver Metastasis

Abstract

Liver metastases are commonly found in advanced cancer patients; however, acute liver failure secondary to diffuse liver infiltration is rare. Small cell lung carcinoma accounts for 15% of lung carcinomas. We describe the ninth case of small cell lung carcinoma massively metastatic to the liver, reported in the scientific literature, with sudden clinical onset and death after a few days. An autopsy was performed to understand the cause of death.

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Published

2019-08-15

Issue

Section

Article / Autopsy Case Report

How to Cite

Guerriero, M., Carbone, A., Colasurdo, F., Pellegrini, V., & Pollio, A. M. (2019). Sudden onset acute liver failure in a patient with clinically occult small cell lung carcinoma: autopsy report and review of the medical literature. Autopsy and Case Reports, 9(2), e2019089. https://doi.org/10.4322/acr.2019.089