Maxillary dentigerous cyst showing squamous odontogenic tumor‑like proliferation: surgical approach and literature review

Authors

  • Camila de Oliveira Barbeiro Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Medicina Oral, Departamento de Diagnóstico e Cirurgia, Araraquara, SP, Brasil https://orcid.org/0000-0002-8166-0101
  • Roberto Henrique Barbeiro Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Medicina Oral, Departamento de Diagnóstico e Cirurgia, Araraquara, SP, Brasil https://orcid.org/0000-0002-9037-0763
  • Heitor Albergoni da Silveira Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Medicina Oral, Departamento de Diagnóstico e Cirurgia, Araraquara, SP, Brasil https://orcid.org/0000-0002-6724-3504
  • Luciana Yamamoto de Almeida Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Medicina Oral, Departamento de Diagnóstico e Cirurgia, Araraquara, SP, Brasil https://orcid.org/0000-0001-5403-4052
  • Jorge Esquiche León Universidade de São Paulo (USP), Faculdade de Odontologia de Ribeirão Preto, Patologia Oral, Departamento de Estomatologia, Saúde Coletiva e Odontologia Legal, Ribeirão Preto, SP, Brasil https://orcid.org/0000-0002-9668-5870
  • Andreia Bufalino Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Medicina Oral, Departamento de Diagnóstico e Cirurgia, Araraquara, SP, Brasil https://orcid.org/0000-0002-6714-6253

DOI:

https://doi.org/10.4322/acr.2021.302

Keywords:

Squamous odontogenic tumor, odontogenic cysts, dentigerous cyst, histology

Abstract

Squamous odontogenic tumor (SOT) is a rare benign neoplasm of the jaw that likely arises from remnants of the dental lamina. It is a slow-growing lesion, with a radiolucent appearance in the central variant. Microscopically, SOT shows islands of squamous epithelium supported by fibrous stroma. In rare cases, squamous odontogenic tumor-like proliferation (SOT-LP) can be observed arising from odontogenic cysts (SOT-LPOC). Herein, we describe the case of a 42-year-old man who presented with discreet bleeding in the maxillary gingiva. Imaging revealed a well-defined, ovoid-shaped lesion with sclerotic margins involving tooth #18 in the intraosseous location. Fine needle aspiration supported the cystic nature of the lesion. After surgery, microscopy revealed a dentigerous cyst showing SOT-LP features. There was no recurrence after a 3-year follow-up. To the best of our knowledge, this is the first report of a dentigerous cyst showing SOT-LP features in the maxilla. Such cysts should be identified to avoid misdiagnosis, with the finding having therapeutic and prognostic implications.

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References

Pullon PA, Shafer WG, Elzay RP, Kerr DA, Corio RL. Squamous odontogenic tumor. Report of six cases of a previously undescribed lesion. Oral Surg Oral Med Oral Pathol. 1975;40(5):616-30. http://dx.doi.org/10.1016/0030-4220(75)90372-2. PMid:1059063.

Elmuradi S, Mair Y, Suresh L, DeSantis J, Neiders M, Aguirre A. Multicentric squamous odontogenic tumor: a case report and review of the literature. Head Neck Pathol. 2017;11(2):168-74. http://dx.doi.org/10.1007/s12105-016-0753-2. PMid:27632187.

Chrcanovic BR, Gomez RS. Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 cases reported in the literature. J Craniomaxillofac Surg. 2018;46(3):504-10. http://dx.doi.org/10.1016/j.jcms.2017.12.023. PMid:29311021.

Parmar RM, Brannon RB, Fowler CB. Squamous odontogenic tumor-like proliferations in radicular cysts: a clinicopathologic study of forty-two cases. J Endod. 2011;37(5):623-6. http://dx.doi.org/10.1016/j.joen.2011.02.010. PMid:21496660.

Wright JM Jr. Squamous odontogenic tumorlike proliferations in odontogenic cysts. Oral Surg Oral Med Oral Pathol. 1979;47(4):354-8. http://dx.doi.org/10.1016/0030-4220(79)90259-7. PMid:285403.

Leventon GS, Happonen RP, Newland JR. Squamous odontogenic tumor. Am J Surg Pathol. 1981;5(7):671-7. http://dx.doi.org/10.1097/00000478-198110000-00009. PMid:7337159.

Fay JT, Banner J, Rothouse L, Kolas S, Klinger BJ, Sayers RJ. Squamous odontogenic tumors arising in odontogenic cysts. J Oral Med. 1981;36(2):35-8. PMid:6942129.

Simon JH, Jensen JL. Squamous odontogenic tumor-like proliferations in periapical cysts. J Endod. 1985;11(10):446-8. http://dx.doi.org/10.1016/S0099-2399(85)80084-4. PMid:3865990.

Sala-Pérez S, Marco-Molina V, Gay-Escoda C. Squamous odontogenic tumor-like proliferation in a radicular cyst: a case report. J Clin Exp Dent. 2013;5(5):e298-301. http://dx.doi.org/10.4317/jced.51056. PMid:24455099.

Laungani N, Hengen S, Nester C, Smith MH. Pericoronal radiolucency surrounding an impacted mandibular molar. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;129(4):286-9. http://dx.doi.org/10.1016/j.oooo.2019.01.070. PMid:31351918.

Unal T, Gomel M, Gunel O. Squamous odontogenic tumor-like islands in a radicular cyst: report of a case. J Oral Maxillofac Surg. 1987;45(4):346-9. http://dx.doi.org/10.1016/0278-2391(87)90358-2. PMid:3470457.

Anjana R, Murali N, Malathi N, Suresh RR. Management of a rare case of peripheral squamous odontogenic tumor of the gingiva. J Indian Soc Periodontol. 2016;20(3):336-9. PMid:27563210.

Swinson BD, Jerjes W, Thomas GJ. Squamous cell carcinoma arising in a residual odontogenic cyst: case report. J Oral Maxillofac Surg. 2005;63(8):1231-3. http://dx.doi.org/10.1016/j.joms.2005.04.016. PMid:16094597.

Oliveira JA, Costa IM, Loyola AM. Squamous odontogenic tumor-like proliferations (SOT-LP) versus intraosseous squamous cell carcinoma in residual cyst. J Oral Maxillofac Surg. 2006;64(8):1325. http://dx.doi.org/10.1016/j.joms.2006.04.026. PMid:16860239.

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Published

2021-08-25

Issue

Vol. 11 (2021)

Section

Clinical Case Report and Review

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How to Cite

de Oliveira Barbeiro, C. ., Henrique Barbeiro, R. ., Albergoni da Silveira, H. ., Yamamoto de Almeida, L. ., Esquiche León, J. ., & Bufalino, A. . (2021). Maxillary dentigerous cyst showing squamous odontogenic tumor‑like proliferation: surgical approach and literature review. Autopsy and Case Reports, 11, e2021302. https://doi.org/10.4322/acr.2021.302