Tribute to the centenary of Waterhouse-Friderichsen syndrome: a case report

Authors

  • Huei Hsin Shieh Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Patrícia Freitas Góes Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Albert Bousso Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Fabiana Roberto Lima Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Maria Cláudia Nogueira Zerbini Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.

DOI:

https://doi.org/10.4322/acr.2016.015

Keywords:

Waterhouse-Friderichsen Syndrome, Purpura fulminans, Shock septic, Meningitis meningococcal, Adrenal insufficiency.

Abstract

The Waterhouse-Friderichsen Syndrome was first reported by Rupert Waterhouse exactly 100 years ago on March 4th, 1911. It is an acute infectious disease that generally progress to a lethal outcome despite the adoption of all available resources of an intensive therapy unit. We describe an illustrative
case of meningococcal meningitis C. This report details the clinical, pathological and therapeutic features of a patient of 3 years and 4 months who had a fulminating evolution, despite adherence to updated recommendations for the treatment of pediatric septic shock. We stress the little change in clinical
and pathological aspects of Waterhouse-Friderichsen Syndrome during the last 100 years, despite tremendous advances in therapy and technology of the pediatric intensive care.

Downloads

Download data is not yet available.

Author Biographies

  • Huei Hsin Shieh, Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
    Divisão de Clínica Pediátrica – Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Patrícia Freitas Góes, Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
    Divisão de Clínica Pediátrica – Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Albert Bousso, Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
    Divisão de Clínica Pediátrica – Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Fabiana Roberto Lima, Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
    Serviço de Anatomia Patológica – Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
  • Maria Cláudia Nogueira Zerbini, Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.
    Serviço de Anatomia Patológica – Hospital Universitário – Universidade de São Paulo – São Paulo/SP – Brasil.

Downloads

Published

2011-03-08

Issue

Vol. 1 No. 1 (2011)

Section

Article / Autopsy Case Report

License

Authors of articles published by Autopsy and Case Report retain the copyright of their work without restrictions, licensing it under the Creative Commons Attribution License - CC-BY, which allows articles to be re-used and re-distributed without restriction, as long as the original work is correctly cited.

How to Cite

Shieh, H. H., Góes, P. F., Bousso, A., Lima, F. R., & Zerbini, M. C. N. (2011). Tribute to the centenary of Waterhouse-Friderichsen syndrome: a case report. Autopsy and Case Reports, 1(1). https://doi.org/10.4322/acr.2016.015