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Minimal inhibitory concentration (MIC) determination of disinfectant and/or sterilizing agents


 
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1. Title Title of document Minimal inhibitory concentration (MIC) determination of disinfectant and/or sterilizing agents
 
2. Creator Author's name, affiliation, country Priscila Gava Mazzola; State University of Campinas; Faculty of Medical Sciences; Department of Clinical Pathology
 
2. Creator Author's name, affiliation, country Angela Faustino Jozala; University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Biochemical-Pharmaceutical Technology
 
2. Creator Author's name, affiliation, country Letícia Célia de Lencastre Novaes; University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Biochemical-Pharmaceutical Technology
 
2. Creator Author's name, affiliation, country Patricia Moriel; State University of Campinas; Faculty of Medical Sciences; Department of Clinical Pathology
 
2. Creator Author's name, affiliation, country Thereza Christina Vessoni Penna; University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Biochemical-Pharmaceutical Technology
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Minimal inhibitory concentration;Disinfectant agents;Sterilizing agents;Sanitation^i1^sprogr
 
4. Description Abstract Due to the growing number of outbreaks of infection in hospital and nurseries, it becomes essential to set up a sanitation program that indicates that the appropriate chemical agent was chosen for application in the most effective way. Validating the effectiveness of decontamination and disinfection is an important and often challenging task. In order to study and compare the behavior of selected microorganisms, they were submitted to minimal inhibitory concentration (MIC). The MIC intervals, which reduced bacteria populations over 6 log10, were: 59 to 156 mg/L of quaternary ammonium compounds (QACs); 63 to 10000 mg/L of chlorhexidine; 1375 to 3250 mg/L of glutaraldehyde; 39 to 246 mg/L of formaldehyde; 43750 to 87500 mg/L of ethanol; 1250 to 6250 mg/L of iodine in polyvinyl-pyrolidone complexes, 150 to 4491 mg/L of chlorine-releasing-agents (CRAs) and 469 to 2500 mg/L of hydrogen peroxide. Chlorhexidine showed non inhibitory activity over germinating spores. A. calcoaceticus showed resistance to the majority of the agents tested, followed by E. cloacae and S. marcescens.
 
5. Publisher Organizing agency, location Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2009-06-01
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://www.revistas.usp.br/bjps/article/view/10677
 
10. Identifier Digital Object Identifier (DOI) http://dx.doi.org/10.1590/S1984-82502009000200008
 
11. Source Title; vol., no. (year) Brazilian Journal of Pharmaceutical Sciences (Impresso); Vol 45, No 2 (2009)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2017 Brazilian Journal of Pharmaceutical Sciences (Impresso)
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