Common calcaneal tendon repair with glycerin-preserved carotid artery xenografts and autologous bone marrow mononuclear cells in rabbits

Authors

  • Robson José Gomes de Melo Secretaria Municipal dos Direitos dos Animais
  • Gentil Ferreira Gonçalves Universidade Federal da Fronteira Sul, Curso de Medicina Veterinária
  • Duvaldo Eurides Universidade Federal de Uberlândia, Faculdade de Medicina Veterinária
  • Patricia Romagnolli Universidade Federal da Fronteira Sul, Curso de Medicina Veterinária
  • Marshal Costa Leme Universidade Federal do Espírito Santo, Curso de Medicina Veterinária
  • Eduardo José de Almeida Araújo Universidade Estadual de Londrina
  • Campo Amor Vieira da Cunha Neto Universidade Estadual Paulista “Júlio de Mesquita Filho”, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Veterinária

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2016.100404

Keywords:

Tendon, Surgery, Adult stem cells

Abstract

Fifteen adult rabbits were used to evaluate the repair of experimental common calcaneal tendon defects treated with glycerin-preserved canine carotid artery xenografts alone or associated with autologous mononuclear bone marrow cells (AMCs). Rabbits were submitted to daily clinical examination; implanted sites were analyzed under light microscopy within 15, 30 and 60 days of surgery. Pelvic limbs receiving xenografts associated with AMCs had better physical performance as well as higher collagen fiber, fibroblast, lymphocyte and new vessel counts at all postoperative time points considered. Glycerin-preserved canine carotid artery xenografts associated with AMCs constituted an effective method for common calcaneal tendon repair in rabbits. 

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Published

2017-02-02

How to Cite

Melo, R. J. G. de, Gonçalves, G. F., Eurides, D., Romagnolli, P., Leme, M. C., Araújo, E. J. de A., & Cunha Neto, C. A. V. da. (2017). Common calcaneal tendon repair with glycerin-preserved carotid artery xenografts and autologous bone marrow mononuclear cells in rabbits. Brazilian Journal of Veterinary Research and Animal Science, 53(4), 1-9. https://doi.org/10.11606/issn.1678-4456.bjvras.2016.100404

Issue

Vol. 53 No. 4 (2016)

Section

FULL ARTICLE

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

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