The role of prostaglandin F2α on ovulation and LH release in cows

Authors

  • Natália Ávila de Castro Universidade Federal de Pelotas, Pelotas – RS, Brazil https://orcid.org/0000-0002-7710-6044
  • Carlos Eduardo Porciuncula Leonardi University of Saskatchewan, Saskatoon – SK, Canada
  • Jaswant Singh University of Saskatchewan, Saskatoon – SK, Canada
  • Augusto Schneider Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Paulo Bayard Gonçalves Universidade Federal de Santa Maria, Santa Maria – RS, Brazil
  • Fernando Caetano Oliveira Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Camila Amaral D’Ávila Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Rogério Ferreira Universidade Estadual de Santa Catarina, Chapecó – SC, Brazil
  • Bernardo Garziera Gasperin Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Elizângela Mírian Moreira Embrapa-Empresa Brasileira de Pesquisa Agropecuária, Porto Velho – RO, Brazil
  • Jéssica de Souza Andrade Bionorte-Rede de Biodiversidade e Biotecnologia da Amazônia Legal, Programa de Pós-graduação em Biodiversidade e Biotecnologia da Amazônia Legal, Porto Velho – RO, Brazil
  • Luiz Francisco Machado Pfeifer Embrapa-Empresa Brasileira de Pesquisa Agropecuária, Porto Velho – RO, Brazil https://orcid.org/0000-0003-2069-951X

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2021.175001

Keywords:

Cow, Ovary, Pituitary, Prostaglandin, Reproduction

Abstract

This study aimed to evaluate the role of prostaglandin F2α (PGF) on ovulation. In Experiment 1, cows were randomly allocated to two treatments to receive 150 μg of d-Cloprostenol (PGF Group, n = 12) or 2 mL of NaCl 0.9% (Control Group, n = 11) and CIDRs, were removed 4 days later. No cow ovulated in Control and PGF groups. In Experiment 2, cows were randomly separated into two experimental groups to receive 4 injections of 150 μg of d-Cloprostenol (n = 9) or 2 mL of NaCL 0.9% (n = 9). In this experiment, ovulation was not observed in any cows. In Experiment 3, ovariectomized cows receive three injections of 300μg of PGF analog (PGF Group, n = 5), 100μg of Lecirelin (GnRH Group, n = 5) or 2 mL of PBS (Control Group, n = 4). The LH concentration was higher (P <0.0001) in cows from the GnRH group than in the PGF and Control groups. In experiment 4, cows with preovulatory follicles (>11.5 mm) were treated with Saline (Control Group, n = 6); Lecirelin (GnRH Group, n = 7) or Cloprostenol Sodium (PGF Group, n = 6). There was a significant increase in the vascular area of follicles from 0 to 24 h in GnRH and PGF treatments. In conclusion, PGF was not able to induce ovulation in cows with high or low plasma progesterone concentration. Additionally, PGF alone was not able to induce LH release and follicle luteinization, but increased follicular vascularization.

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Published

2021-04-01

Issue

Vol. 58 (2021)

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FULL ARTICLE

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How to Cite

1.
Castro N Ávila de, Leonardi CEP, Singh J, Schneider A, Gonçalves PB, Oliveira FC, et al. The role of prostaglandin F2α on ovulation and LH release in cows. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2021 Apr. 1 [cited 2024 Apr. 19];58:e175001. Available from: https://www.revistas.usp.br/bjvras/article/view/175001