Influence of Enzootic Bovine Leukosis on phagocytic function of circulating leukocytes from animals with persistent lymphocytosis

Authors

  • Milton Ricardo Azedo Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Cristina de Oliveira Massoco Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY, USA
  • Maiara Garcia Blagitz Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Bárbara Gabriela Soares Sanches Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Fernando Nogueira de Souza Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Camila Freitas Batista Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Mônica Sakai Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Luiz Carlos de Sá-Rocha Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • José Roberto Kfoury Junior Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia, São Paulo, SP
  • Cláudia Regina Stricagnolo Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Fernando José Benesi Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP
  • Alice Maria Melville Paiva Della Libera Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Médica, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2008.26681

Keywords:

Bovine, Leukocytes, Phagocytosis, Enzootic Bovine Leukosis, Flow Cytometry

Abstract

This study evaluated the phagocytosis of propidium iodide-labeled Staphylococcus aureus (PI-Sa) by circulating leukocytes obtained from five Enzootic Bovine Leukosis (EBL)-negative cows, five naturally EBL-infected, non-lymphocytotic cows, and five EBL-positive cows with persistent lymphocytosis (PL), analyzed by flow cytometry. Among cells obtained from EBL-infected cows, presenting PL, the percentage of leukocytes carrying out phagocytosis (7.20%), was smaller (p=0.047) than that verified among cells obtained from non-infected (12.90%), and from BLV-infected, non-lymphocytotic cows (14.70%). Furthermore, leukocytes obtained from EBL-infected cows, presenting PL, showed smaller phagocytosis intensity (characterized by the intensity of propidium iodide fluorescence) than leukocytes obtained from non-infected and from EBL-infected, non-lymphocytotic, cows (p<0.001). Therefore, results show a decreased phagocytic function among circulating leukocytes obtained from BLV-infected, lymphocytotic cows.

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Published

2008-10-01

How to Cite

Azedo, M. R., Massoco, C. de O., Blagitz, M. G., Sanches, B. G. S., Souza, F. N. de, Batista, C. F., Sakai, M., Sá-Rocha, L. C. de, Kfoury Junior, J. R., Stricagnolo, C. R., Benesi, F. J., & Libera, A. M. M. P. D. (2008). Influence of Enzootic Bovine Leukosis on phagocytic function of circulating leukocytes from animals with persistent lymphocytosis. Brazilian Journal of Veterinary Research and Animal Science, 45(5), 390-397. https://doi.org/10.11606/issn.1678-4456.bjvras.2008.26681

Issue

Vol. 45 No. 5 (2008)

Section

UNDEFINIED

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

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